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Year | Number of Results |
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2019 | 1 |
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The C9orf72 repeat expansion disrupts nucleocytoplasmic transport.
Nature. 2015 Sep 3;525(7567):56-61. doi: 10.1038/nature14973. Epub 2015 Aug 26.
Nature. 2015.
PMID: 26308891
Free PMC article.
Synaptic dysfunction induced by glycine-alanine dipeptides in C9orf72-ALS/FTD is rescued by SV2 replenishment.
Jensen BK, Schuldi MH, McAvoy K, Russell KA, Boehringer A, Curran BM, Krishnamurthy K, Wen X, Westergard T, Ma L, Haeusler AR, Edbauer D, Pasinelli P, Trotti D.
Jensen BK, et al.
EMBO Mol Med. 2020 May 8;12(5):e10722. doi: 10.15252/emmm.201910722. Epub 2020 Apr 29.
EMBO Mol Med. 2020.
PMID: 32347002
Free PMC article.
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The effects of molecular crowding and CpG hypermethylation on DNA G-quadruplexes formed by the C9orf72 nucleotide repeat expansion.
Ozcan KA, Ghaffari LT, Haeusler AR.
Ozcan KA, et al.
Sci Rep. 2021 Dec 1;11(1):23213. doi: 10.1038/s41598-021-02041-4.
Sci Rep. 2021.
PMID: 34853325
Free PMC article.
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Repeat-associated non-AUG translation in C9orf72-ALS/FTD is driven by neuronal excitation and stress.
Westergard T, McAvoy K, Russell K, Wen X, Pang Y, Morris B, Pasinelli P, Trotti D, Haeusler A.
Westergard T, et al.
EMBO Mol Med. 2019 Feb;11(2):e9423. doi: 10.15252/emmm.201809423.
EMBO Mol Med. 2019.
PMID: 30617154
Free PMC article.
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Targeting TNFα produced by astrocytes expressing amyotrophic lateral sclerosis-linked mutant fused in sarcoma prevents neurodegeneration and motor dysfunction in mice.
Jensen BK, McAvoy KJ, Heinsinger NM, Lepore AC, Ilieva H, Haeusler AR, Trotti D, Pasinelli P.
Jensen BK, et al.
Glia. 2022 Jul;70(7):1426-1449. doi: 10.1002/glia.24183. Epub 2022 Apr 26.
Glia. 2022.
PMID: 35474517
Free PMC article.
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