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Design, Synthesis, Antiproliferative Actions, and DFT Studies of New Bis-Pyrazoline Derivatives as Dual EGFR/BRAFV600E Inhibitors.
Int J Mol Sci. 2023 May 22;24(10):9104. doi: 10.3390/ijms24109104.
Int J Mol Sci. 2023.
PMID: 37240450
Free PMC article.
Metabolites Profiling and In Vitro Biological Characterization of Different Fractions of Cliona sp. Marine Sponge from the Red Sea Egypt.
Hassan WHB, El Sayed ZI, Al-Wahaibi LH, Abdel-Aal MM, Abdel-Mageed WM, Abdelsalam E, Abdelaziz S.
Hassan WHB, et al.
Molecules. 2023 Feb 8;28(4):1643. doi: 10.3390/molecules28041643.
Molecules. 2023.
PMID: 36838631
Free PMC article.
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Quinazolin-4-one/3-cyanopyridin-2-one Hybrids as Dual Inhibitors of EGFR and BRAFV600E: Design, Synthesis, and Antiproliferative Activity.
Al-Wahaibi LH, Hisham M, Abou-Zied HA, Hassan HA, Youssif BGM, Bräse S, Hayallah AM, Abdel-Aziz M.
Al-Wahaibi LH, et al.
Pharmaceuticals (Basel). 2023 Oct 26;16(11):1522. doi: 10.3390/ph16111522.
Pharmaceuticals (Basel). 2023.
PMID: 38004388
Free PMC article.
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Design, Synthesis, and Biological Evaluation of Indole-2-carboxamides as Potential Multi-Target Antiproliferative Agents.
Al-Wahaibi LH, Mohammed AF, Abdelrahman MH, Trembleau L, Youssif BGM.
Al-Wahaibi LH, et al.
Pharmaceuticals (Basel). 2023 Jul 22;16(7):1039. doi: 10.3390/ph16071039.
Pharmaceuticals (Basel). 2023.
PMID: 37513950
Free PMC article.
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Design, Synthesis, and Biological Evaluation of Novel 3-Cyanopyridone/Pyrazoline Hybrids as Potential Apoptotic Antiproliferative Agents Targeting EGFR/BRAFV600E Inhibitory Pathways.
Al-Wahaibi LH, Abou-Zied HA, Hisham M, Beshr EAM, Youssif BGM, Bräse S, Hayallah AM, Abdel-Aziz M.
Al-Wahaibi LH, et al.
Molecules. 2023 Sep 12;28(18):6586. doi: 10.3390/molecules28186586.
Molecules. 2023.
PMID: 37764362
Free PMC article.
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Design, Synthesis, and Antiproliferative Activity of New 5-Chloro-indole-2-carboxylate and Pyrrolo[3,4-b]indol-3-one Derivatives as Potent Inhibitors of EGFRT790M/BRAFV600E Pathways.
Al-Wahaibi LH, Mohammed AF, Abdelrahman MH, Trembleau L, Youssif BGM.
Al-Wahaibi LH, et al.
Molecules. 2023 Jan 28;28(3):1269. doi: 10.3390/molecules28031269.
Molecules. 2023.
PMID: 36770936
Free PMC article.
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One-Pot Synthesis of 1-Thia-4-azaspiro[4.4/5]alkan-3-ones via Schiff Base: Design, Synthesis, and Apoptotic Antiproliferative Properties of Dual EGFR/BRAFV600E Inhibitors.
Al-Wahaibi LH, El-Sheref EM, Hammouda MM, Youssif BGM.
Al-Wahaibi LH, et al.
Pharmaceuticals (Basel). 2023 Mar 22;16(3):467. doi: 10.3390/ph16030467.
Pharmaceuticals (Basel). 2023.
PMID: 36986566
Free PMC article.
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