P01 GM032165/GM/NIGMS NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2002	1
2004	1
2006	5
2007	4
2008	12
2009	10
2010	17
2011	23
2012	20
2013	12
2014	8
2015	6
2016	2
2018	1
2020	1
2021	1
2022	3
2023	1
2024	0

1

Chapter 11 - Reconstitution of membrane proteins in phospholipid bilayer nanodiscs.

Ritchie TK, Grinkova YV, Bayburt TH, Denisov IG, Zolnerciks JK, Atkins WM, Sligar SG. Ritchie TK, et al. Methods Enzymol. 2009;464:211-31. doi: 10.1016/S0076-6879(09)64011-8. Methods Enzymol. 2009. PMID: 19903557 Free PMC article.

2

Rearrangement reactions catalyzed by cytochrome P450s.

Ortiz de Montellano PR, Nelson SD. Ortiz de Montellano PR, et al. Arch Biochem Biophys. 2011 Mar 1;507(1):95-110. doi: 10.1016/j.abb.2010.10.016. Epub 2010 Oct 29. Arch Biochem Biophys. 2011. PMID: 20971058 Free PMC article. Review.

3

Interactions of cytochrome P450s with their ligands.

Conner KP, Woods CM, Atkins WM. Conner KP, et al. Arch Biochem Biophys. 2011 Mar 1;507(1):56-65. doi: 10.1016/j.abb.2010.10.006. Epub 2010 Oct 19. Arch Biochem Biophys. 2011. PMID: 20939998 Free PMC article. Review.

4

Mechanism-based inactivation of CYP450 enzymes: a case study of lapatinib.

Ho HK, Chan JC, Hardy KD, Chan EC. Ho HK, et al. Drug Metab Rev. 2015 Feb;47(1):21-8. doi: 10.3109/03602532.2014.1003648. Epub 2015 Feb 2. Drug Metab Rev. 2015. PMID: 25639891 Free PMC article. Review.

5

Drug interactions at the blood-brain barrier: fact or fantasy?

Eyal S, Hsiao P, Unadkat JD. Eyal S, et al. Pharmacol Ther. 2009 Jul;123(1):80-104. doi: 10.1016/j.pharmthera.2009.03.017. Epub 2009 Apr 22. Pharmacol Ther. 2009. PMID: 19393264 Free PMC article. Review.

6

Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2C9 and HLA-B Genotypes and Phenytoin Dosing: 2020 Update.

Karnes JH, Rettie AE, Somogyi AA, Huddart R, Fohner AE, Formea CM, Ta Michael Lee M, Llerena A, Whirl-Carrillo M, Klein TE, Phillips EJ, Mintzer S, Gaedigk A, Caudle KE, Callaghan JT. Karnes JH, et al. Clin Pharmacol Ther. 2021 Feb;109(2):302-309. doi: 10.1002/cpt.2008. Epub 2020 Sep 6. Clin Pharmacol Ther. 2021. PMID: 32779747 Free PMC article. Review.

7

Rationalization and prediction of in vivo metabolite exposures: the role of metabolite kinetics, clearance predictions and in vitro parameters.

Lutz JD, Fujioka Y, Isoherranen N. Lutz JD, et al. Expert Opin Drug Metab Toxicol. 2010 Sep;6(9):1095-109. doi: 10.1517/17425255.2010.497487. Expert Opin Drug Metab Toxicol. 2010. PMID: 20557268 Free PMC article. Review.

8

Pharmacokinetic Modeling of Warfarin ІI - Model-based Analysis of Warfarin Metabolites following Warfarin Administered either Alone or Together with Fluconazole or Rifampin.

Cheng S, Flora DR, Rettie AE, Brundage RC, Tracy TS. Cheng S, et al. Drug Metab Dispos. 2022 Jul 7;50(9):1302-11. doi: 10.1124/dmd.122.000877. Online ahead of print. Drug Metab Dispos. 2022. PMID: 35798368 Free PMC article.

9

Effect of CYP3A5 expression on the inhibition of CYP3A-catalyzed drug metabolism: impact on modeling CYP3A-mediated drug-drug interactions.

Shirasaka Y, Chang SY, Grubb MF, Peng CC, Thummel KE, Isoherranen N, Rodrigues AD. Shirasaka Y, et al. Drug Metab Dispos. 2013 Aug;41(8):1566-74. doi: 10.1124/dmd.112.049940. Epub 2013 May 30. Drug Metab Dispos. 2013. PMID: 23723360 Free PMC article.

10

Importance of multi-p450 inhibition in drug-drug interactions: evaluation of incidence, inhibition magnitude, and prediction from in vitro data.

Isoherranen N, Lutz JD, Chung SP, Hachad H, Levy RH, Ragueneau-Majlessi I. Isoherranen N, et al. Chem Res Toxicol. 2012 Nov 19;25(11):2285-300. doi: 10.1021/tx300192g. Epub 2012 Sep 27. Chem Res Toxicol. 2012. PMID: 22823924 Free PMC article. Review.

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