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Synthesis of N-substituted 2-[(1E)-alkenyl]-4-(1H)-quinolone derivatives as antimycobacterial agents against non-tubercular mycobacteria.
Eur J Med Chem. 2011 Jun;46(6):2091-101. doi: 10.1016/j.ejmech.2011.02.062. Epub 2011 Mar 3.
Eur J Med Chem. 2011.
PMID: 21429630
Free PMC article.
Design, synthesis and antimycobacterial activities of 1-methyl-2-alkenyl-4(1H)-quinolones.
Wube AA, Hüfner A, Thomaschitz C, Blunder M, Kollroser M, Bauer R, Bucar F.
Wube AA, et al.
Bioorg Med Chem. 2011 Jan 1;19(1):567-79. doi: 10.1016/j.bmc.2010.10.060. Epub 2010 Nov 3.
Bioorg Med Chem. 2011.
PMID: 21106378
Free PMC article.
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Synthesis and antibacterial evaluation of a new series of N-Alkyl-2-alkynyl/(E)-alkenyl-4-(1H)-quinolones.
Wube A, Guzman JD, Hüfner A, Hochfellner C, Blunder M, Bauer R, Gibbons S, Bhakta S, Bucar F.
Wube A, et al.
Molecules. 2012 Jul 9;17(7):8217-40. doi: 10.3390/molecules17078217.
Molecules. 2012.
PMID: 22777190
Free PMC article.
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Interaction of N-methyl-2-alkenyl-4-quinolones with ATP-dependent MurE ligase of Mycobacterium tuberculosis: antibacterial activity, molecular docking and inhibition kinetics.
Guzman JD, Wube A, Evangelopoulos D, Gupta A, Hüfner A, Basavannacharya C, Rahman MM, Thomaschitz C, Bauer R, McHugh TD, Nobeli I, Prieto JM, Gibbons S, Bucar F, Bhakta S.
Guzman JD, et al.
J Antimicrob Chemother. 2011 Aug;66(8):1766-72. doi: 10.1093/jac/dkr203. Epub 2011 May 28.
J Antimicrob Chemother. 2011.
PMID: 21622974
Free PMC article.
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