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Chromosome-scale assembly and whole-genome sequencing of 266 giant panda roundworms provide insights into their evolution, adaptation and potential drug targets.
Han L, Lan T, Li D, Li H, Deng L, Peng Z, He S, Zhou Y, Han R, Li L, Lu Y, Lu H, Wang Q, Yang S, Zhu Y, Huang Y, Cheng X, Yu J, Wang Y, Sun H, Chai H, Yang H, Xu X, Lisby M, Liu Q, Kristiansen K, Liu H, Hou Z. Han L, et al. Mol Ecol Resour. 2022 Feb;22(2):768-785. doi: 10.1111/1755-0998.13504. Epub 2021 Oct 28. Mol Ecol Resour. 2022. PMID: 34549895 Free PMC article.
Equus roundworms (Parascaris univalens) are undergoing rapid divergence while genes involved in metabolic as well as anthelminic resistance are under positive selection.
Han L, Lan T, Lu Y, Zhou M, Li H, Lu H, Wang Q, Li X, Du S, Guan C, Zhang Y, Sahu SK, Qian P, Zhang S, Zhou H, Guo W, Chai H, Wang S, Liu Q, Liu H, Hou Z. Han L, et al. BMC Genomics. 2022 Jul 4;23(1):489. doi: 10.1186/s12864-022-08702-6. BMC Genomics. 2022. PMID: 35787772 Free PMC article.