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Page 1
Proteostasis and the aging proteome in health and disease.
Morimoto RI, Cuervo AM. Morimoto RI, et al. J Gerontol A Biol Sci Med Sci. 2014 Jun;69 Suppl 1(Suppl 1):S33-8. doi: 10.1093/gerona/glu049. J Gerontol A Biol Sci Med Sci. 2014. PMID: 24833584 Free PMC article. Review.
How the nucleus copes with proteotoxic stress.
Shibata Y, Morimoto RI. Shibata Y, et al. Curr Biol. 2014 May 19;24(10):R463-74. doi: 10.1016/j.cub.2014.03.033. Curr Biol. 2014. PMID: 24845679 Free PMC article. Review.
Serotonergic signalling suppresses ataxin 3 aggregation and neurotoxicity in animal models of Machado-Joseph disease.
Teixeira-Castro A, Jalles A, Esteves S, Kang S, da Silva Santos L, Silva-Fernandes A, Neto MF, Brielmann RM, Bessa C, Duarte-Silva S, Miranda A, Oliveira S, Neves-Carvalho A, Bessa J, Summavielle T, Silverman RB, Oliveira P, Morimoto RI, Maciel P. Teixeira-Castro A, et al. Brain. 2015 Nov;138(Pt 11):3221-37. doi: 10.1093/brain/awv262. Epub 2015 Sep 15. Brain. 2015. PMID: 26373603 Free PMC article.
Small-molecule proteostasis regulators for protein conformational diseases.
Calamini B, Silva MC, Madoux F, Hutt DM, Khanna S, Chalfant MA, Saldanha SA, Hodder P, Tait BD, Garza D, Balch WE, Morimoto RI. Calamini B, et al. Nat Chem Biol. 2011 Dec 25;8(2):185-96. doi: 10.1038/nchembio.763. Nat Chem Biol. 2011. PMID: 22198733 Free PMC article.
13 results