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Astrocyte biomarker signatures of amyloid-β and tau pathologies in Alzheimer's disease.
Ferrari-Souza JP, Ferreira PCL, Bellaver B, Tissot C, Wang YT, Leffa DT, Brum WS, Benedet AL, Ashton NJ, De Bastiani MA, Rocha A, Therriault J, Lussier FZ, Chamoun M, Servaes S, Bezgin G, Kang MS, Stevenson J, Rahmouni N, Pallen V, Poltronetti NM, Klunk WE, Tudorascu DL, Cohen AD, Villemagne VL, Gauthier S, Blennow K, Zetterberg H, Souza DO, Karikari TK, Zimmer ER, Rosa-Neto P, Pascoal TA. Ferrari-Souza JP, et al. Mol Psychiatry. 2022 Nov;27(11):4781-4789. doi: 10.1038/s41380-022-01716-2. Epub 2022 Aug 10. Mol Psychiatry. 2022. PMID: 35948658 Free PMC article.
The GABAergic system in Alzheimer's disease: a systematic review with meta-analysis.
Carello-Collar G, Bellaver B, Ferreira PCL, Ferrari-Souza JP, Ramos VG, Therriault J, Tissot C, De Bastiani MA, Soares C, Pascoal TA, Rosa-Neto P, Souza DO, Zimmer ER. Carello-Collar G, et al. Mol Psychiatry. 2023 Dec;28(12):5025-5036. doi: 10.1038/s41380-023-02140-w. Epub 2023 Jul 7. Mol Psychiatry. 2023. PMID: 37419974
CSF p-tau205: a biomarker of tau pathology in Alzheimer's disease.
Lantero-Rodriguez J, Montoliu-Gaya L, Benedet AL, Vrillon A, Dumurgier J, Cognat E, Brum WS, Rahmouni N, Stevenson J, Servaes S, Therriault J, Becker B, Brinkmalm G, Snellman A, Huber H, Kvartsberg H, Ashton NJ, Zetterberg H, Paquet C, Rosa-Neto P, Blennow K. Lantero-Rodriguez J, et al. Acta Neuropathol. 2024 Jan 6;147(1):12. doi: 10.1007/s00401-023-02659-w. Acta Neuropathol. 2024. PMID: 38184490 Free PMC article.
Equivalence of plasma p-tau217 with cerebrospinal fluid in the diagnosis of Alzheimer's disease.
Therriault J, Servaes S, Tissot C, Rahmouni N, Ashton NJ, Benedet AL, Karikari TK, Macedo AC, Lussier FZ, Stevenson J, Wang YT, Fernandez-Arias J, Stevenson A, Socualaya KQ, Haeger A, Nazneen T, Aumont É, Hosseini A, Rej S, Vitali P, Triana-Baltzer G, Kolb HC, Soucy JP, Pascoal TA, Gauthier S, Zetterberg H, Blennow K, Rosa-Neto P. Therriault J, et al. Alzheimers Dement. 2023 Nov;19(11):4967-4977. doi: 10.1002/alz.13026. Epub 2023 Apr 20. Alzheimers Dement. 2023. PMID: 37078495
APOEε4 potentiates amyloid β effects on longitudinal tau pathology.
Ferrari-Souza JP, Bellaver B, Ferreira PCL, Benedet AL, Povala G, Lussier FZ, Leffa DT, Therriault J, Tissot C, Soares C, Wang YT, Chamoun M, Servaes S, Macedo AC, Vermeiren M, Bezgin G, Kang MS, Stevenson J, Rahmouni N, Pallen V, Poltronetti NM, Cohen A, Lopez OL, Klunk WE, Soucy JP, Gauthier S, Souza DO, Triana-Baltzer G, Saad ZS, Kolb HC, Karikari TK, Villemagne VL, Tudorascu DL, Ashton NJ, Zetterberg H, Blennow K, Zimmer ER, Rosa-Neto P, Pascoal TA. Ferrari-Souza JP, et al. Nat Aging. 2023 Oct;3(10):1210-1218. doi: 10.1038/s43587-023-00490-2. Epub 2023 Sep 25. Nat Aging. 2023. PMID: 37749258 Free PMC article.
Plasma p-tau231 and p-tau217 inform on tau tangles aggregation in cognitively impaired individuals.
Ferreira PCL, Therriault J, Tissot C, Ferrari-Souza JP, Benedet AL, Povala G, Bellaver B, Leffa DT, Brum WS, Lussier FZ, Bezgin G, Servaes S, Vermeiren M, Macedo AC, Cabrera A, Stevenson J, Triana-Baltzer G, Kolb H, Rahmouni N, Klunk WE, Lopez OL, Villemagne VL, Cohen A, Tudorascu DL, Zimmer ER, Karikari TK, Ashton NJ, Zetterberg H, Blennow K, Gauthier S, Rosa-Neto P, Pascoal TA. Ferreira PCL, et al. Alzheimers Dement. 2023 Oct;19(10):4463-4474. doi: 10.1002/alz.13393. Epub 2023 Aug 3. Alzheimers Dement. 2023. PMID: 37534889
Soluble amyloid-beta isoforms predict downstream Alzheimer's disease pathology.
Povala G, Bellaver B, De Bastiani MA, Brum WS, Ferreira PCL, Bieger A, Pascoal TA, Benedet AL, Souza DO, Araujo RM, Zatt B, Rosa-Neto P, Zimmer ER; for the Alzheimer’s Disease Neuroimaging Initiative. Povala G, et al. Cell Biosci. 2021 Dec 11;11(1):204. doi: 10.1186/s13578-021-00712-3. Cell Biosci. 2021. PMID: 34895338 Free PMC article.
Plasma pTau-217 and N-terminal tau (NTA) enhance sensitivity to identify tau PET positivity in amyloid-β positive individuals.
Woo MS, Tissot C, Lantero-Rodriguez J, Snellman A, Therriault J, Rahmouni N, Macedo AC, Servaes S, Wang YT, Arias JF, Hosseini SA, Chamoun M, Lussier FZ, Benedet AL, Ashton NJ, Karikari TK, Triana-Baltzer G, Kolb HC, Stevenson J, Mayer C, Kobayashi E, Massarweh G, Friese MA, Pascoal TA, Gauthier S, Zetterberg H, Blennow K, Rosa-Neto P. Woo MS, et al. Alzheimers Dement. 2024 Feb;20(2):1166-1174. doi: 10.1002/alz.13528. Epub 2023 Nov 3. Alzheimers Dement. 2024. PMID: 37920945 Free PMC article.