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Hepatic Wnt1 Inducible Signaling Pathway Protein 1 (WISP-1/CCN4) Associates with Markers of Liver Fibrosis in Severe Obesity.
Pivovarova-Ramich O, Loske J, Hornemann S, Markova M, Seebeck N, Rosenthal A, Klauschen F, Castro JP, Buschow R, Grune T, Lange V, Rudovich N, Ouwens DM. Pivovarova-Ramich O, et al. Cells. 2021 Apr 29;10(5):1048. doi: 10.3390/cells10051048. Cells. 2021. PMID: 33946738 Free PMC article.
For this, human liver biopsies were collected from 35 severely obese humans (BMI 42.5 0.7 kg/m(2), age 46.7 1.8 y, 25.7% males) during bariatric surgery and examined for the expression of CCN4, fibrosis, and inflammation markers. Hepatic stellate LX-2 cells were treated wi …
For this, human liver biopsies were collected from 35 severely obese humans (BMI 42.5 0.7 kg/m(2), age 46.7 1.8 y, 25.7% males) durin …