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Year Number of Results
2020 9
2021 2
2022 3
2023 5
2024 1

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Page 1
The NLRP3-inflammasome as a sensor of organelle dysfunction.
Seoane PI, Lee B, Hoyle C, Yu S, Lopez-Castejon G, Lowe M, Brough D. Seoane PI, et al. J Cell Biol. 2020 Dec 7;219(12):e202006194. doi: 10.1083/jcb.202006194. J Cell Biol. 2020. PMID: 33044555 Free PMC article. Review.
Inhibiting the NLRP3 Inflammasome.
El-Sharkawy LY, Brough D, Freeman S. El-Sharkawy LY, et al. Molecules. 2020 Nov 25;25(23):5533. doi: 10.3390/molecules25235533. Molecules. 2020. PMID: 33255820 Free PMC article. Review.
Characterisation of C101248: A novel selective THIK-1 channel inhibitor for the modulation of microglial NLRP3-inflammasome.
Ossola B, Rifat A, Rowland A, Hunter H, Drinkall S, Bender C, Hamlischer M, Teall M, Burley R, Barker DF, Cadwalladr D, Dickson L, Lawrence JMK, Harvey JRM, Lizio M, Xu X, Kavanagh E, Cheung T, Sheardown S, Lawrence CB, Harte M, Brough D, Madry C, Matthews K, Doyle K, Page K, Powell J, Brice NL, Bürli RW, Carlton MB, Dawson LA. Ossola B, et al. Neuropharmacology. 2023 Feb 15;224:109330. doi: 10.1016/j.neuropharm.2022.109330. Epub 2022 Nov 12. Neuropharmacology. 2023. PMID: 36375694 Free PMC article.
Inhibition of the NLRP3 inflammasome by HSP90 inhibitors.
Nizami S, Arunasalam K, Green J, Cook J, Lawrence CB, Zarganes-Tzitzikas T, Davis JB, Di Daniel E, Brough D. Nizami S, et al. Immunology. 2021 Jan;162(1):84-91. doi: 10.1111/imm.13267. Epub 2020 Oct 30. Immunology. 2021. PMID: 32954500 Free PMC article.
17 results