MR/L016591/1/MRC_/Medical Research Council/United Kingdom[Grants and Funding] - Search Results

Year	Number of Results
2014	2
2015	1
2017	2
2019	1
2021	1
2023	3
2024	0

1

A Critical Balance: dNTPs and the Maintenance of Genome Stability.

Pai CC, Kearsey SE. Pai CC, et al. Genes (Basel). 2017 Jan 31;8(2):57. doi: 10.3390/genes8020057. Genes (Basel). 2017. PMID: 28146119 Free PMC article. Review.

2

Cellular regulation of ribonucleotide reductase in eukaryotes.

Guarino E, Salguero I, Kearsey SE. Guarino E, et al. Semin Cell Dev Biol. 2014 Jun;30:97-103. doi: 10.1016/j.semcdb.2014.03.030. Epub 2014 Apr 2. Semin Cell Dev Biol. 2014. PMID: 24704278 Review.

3

A simple bypass assay for DNA polymerases shows that cancer-associated hypermutating variants exhibit differences in vitro.

Crevel G, Kearsey S, Cotterill S. Crevel G, et al. FEBS J. 2023 Dec;290(24):5744-5758. doi: 10.1111/febs.16936. Epub 2023 Aug 29. FEBS J. 2023. PMID: 37592814 Free PMC article.

4

Using canavanine resistance to measure mutation rates in Schizosaccharomyces pombe.

Pai CC, Heitzer E, Bertrand S, Toumazou S, Humphrey TC, Kearsey SE. Pai CC, et al. PLoS One. 2023 Jan 10;18(1):e0271016. doi: 10.1371/journal.pone.0271016. eCollection 2023. PLoS One. 2023. PMID: 36626373 Free PMC article.

5

POLE mutations in families predisposed to cutaneous melanoma.

Aoude LG, Heitzer E, Johansson P, Gartside M, Wadt K, Pritchard AL, Palmer JM, Symmons J, Gerdes AM, Montgomery GW, Martin NG, Tomlinson I, Kearsey S, Hayward NK. Aoude LG, et al. Fam Cancer. 2015 Dec;14(4):621-8. doi: 10.1007/s10689-015-9826-8. Fam Cancer. 2015. PMID: 26251183

6

Expression of the cancer-associated DNA polymerase ε P286R in fission yeast leads to translesion synthesis polymerase dependent hypermutation and defective DNA replication.

Soriano I, Vazquez E, De Leon N, Bertrand S, Heitzer E, Toumazou S, Bo Z, Palles C, Pai CC, Humphrey TC, Tomlinson I, Cotterill S, Kearsey SE. Soriano I, et al. PLoS Genet. 2021 Jul 6;17(7):e1009526. doi: 10.1371/journal.pgen.1009526. eCollection 2021 Jul. PLoS Genet. 2021. PMID: 34228709 Free PMC article.

7

An essential role for dNTP homeostasis following CDK-induced replication stress.

Pai CC, Hsu KF, Durley SC, Keszthelyi A, Kearsey SE, Rallis C, Folkes LK, Deegan R, Wilkins SE, Pfister SX, De León N, Schofield CJ, Bähler J, Carr AM, Humphrey TC. Pai CC, et al. J Cell Sci. 2019 Mar 25;132(6):jcs226969. doi: 10.1242/jcs.226969. J Cell Sci. 2019. PMID: 30674555 Free PMC article.

8

Set2 Methyltransferase Facilitates DNA Replication and Promotes Genotoxic Stress Responses through MBF-Dependent Transcription.

Pai CC, Kishkevich A, Deegan RS, Keszthelyi A, Folkes L, Kearsey SE, De León N, Soriano I, de Bruin RAM, Carr AM, Humphrey TC. Pai CC, et al. Cell Rep. 2017 Sep 12;20(11):2693-2705. doi: 10.1016/j.celrep.2017.08.058. Cell Rep. 2017. PMID: 28903048 Free PMC article.

9

Homologous recombination suppresses transgenerational DNA end resection and chromosomal instability in fission yeast.

Pai CC, Durley SC, Cheng WC, Chiang NY, Peters J, Kasparek T, Blaikley E, Wee BY, Walker C, Kearsey SE, Buffa F, Murray JM, Humphrey TC. Pai CC, et al. Nucleic Acids Res. 2023 Apr 24;51(7):3205-3222. doi: 10.1093/nar/gkad160. Nucleic Acids Res. 2023. PMID: 36951111 Free PMC article.

10

Real-time imaging of DNA damage in yeast cells using ultra-short near-infrared pulsed laser irradiation.

Guarino E, Cojoc G, García-Ulloa A, Tolić IM, Kearsey SE. Guarino E, et al. PLoS One. 2014 Nov 19;9(11):e113325. doi: 10.1371/journal.pone.0113325. eCollection 2014. PLoS One. 2014. PMID: 25409521 Free PMC article.

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