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Different contributions of chemokine N-terminal features attest to a different ligand binding mode and a bias towards activation of ACKR3/CXCR7 compared with CXCR4 and CXCR3.
Br J Pharmacol. 2018 May;175(9):1419-1438. doi: 10.1111/bph.14132. Epub 2018 Mar 23.
Br J Pharmacol. 2018.
PMID: 29272550
Free PMC article.
Ligand-specific conformational transitions and intracellular transport are required for atypical chemokine receptor 3-mediated chemokine scavenging.
Montpas N, St-Onge G, Nama N, Rhainds D, Benredjem B, Girard M, Hickson G, Pons V, Heveker N.
Montpas N, et al.
J Biol Chem. 2018 Jan 19;293(3):893-905. doi: 10.1074/jbc.M117.814947. Epub 2017 Nov 27.
J Biol Chem. 2018.
PMID: 29180449
Free PMC article.
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