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Page 1
Anucleate platelets generate progeny.
Schwertz H, Köster S, Kahr WH, Michetti N, Kraemer BF, Weitz DA, Blaylock RC, Kraiss LW, Greinacher A, Zimmerman GA, Weyrich AS. Schwertz H, et al. Blood. 2010 May 6;115(18):3801-9. doi: 10.1182/blood-2009-08-239558. Epub 2010 Jan 19. Blood. 2010. PMID: 20086251 Free PMC article.
Loss of the F-BAR protein CIP4 reduces platelet production by impairing membrane-cytoskeleton remodeling.
Chen Y, Aardema J, Kale S, Whichard ZL, Awomolo A, Blanchard E, Chang B, Myers DR, Ju L, Tran R, Reece D, Christensen H, Boukour S, Debili N, Strom TS, Rawlings D, Vázquez FX, Voth GA, Zhu C, Kahr WH, Lam WA, Corey SJ. Chen Y, et al. Blood. 2013 Sep 5;122(10):1695-706. doi: 10.1182/blood-2013-03-484550. Epub 2013 Jul 23. Blood. 2013. PMID: 23881916 Free PMC article.
Mutations in NBEAL2, encoding a BEACH protein, cause gray platelet syndrome.
Kahr WH, Hinckley J, Li L, Schwertz H, Christensen H, Rowley JW, Pluthero FG, Urban D, Fabbro S, Nixon B, Gadzinski R, Storck M, Wang K, Ryu GY, Jobe SM, Schutte BC, Moseley J, Loughran NB, Parkinson J, Weyrich AS, Di Paola J. Kahr WH, et al. Nat Genet. 2011 Jul 17;43(8):738-40. doi: 10.1038/ng.884. Nat Genet. 2011. PMID: 21765413 Free PMC article.