MC_UU_12009/3/MRC_/Medical Research Council/United Kingdom[Grants and Funding] - Search Results

Year	Number of Results
2014	3
2015	5
2016	4
2017	3
2018	2
2019	2
2021	1
2022	1
2024	0

1

α-Globin as a molecular target in the treatment of β-thalassemia.

Mettananda S, Gibbons RJ, Higgs DR. Mettananda S, et al. Blood. 2015 Jun 11;125(24):3694-701. doi: 10.1182/blood-2015-03-633594. Epub 2015 Apr 13. Blood. 2015. PMID: 25869286 Free PMC article. Review.

2

Maintaining memory of silencing at imprinted differentially methylated regions.

Voon HP, Gibbons RJ. Voon HP, et al. Cell Mol Life Sci. 2016 May;73(9):1871-9. doi: 10.1007/s00018-016-2157-6. Epub 2016 Feb 16. Cell Mol Life Sci. 2016. PMID: 26883803 Free PMC article. Review.

3

Understanding α-globin gene regulation and implications for the treatment of β-thalassemia.

Mettananda S, Gibbons RJ, Higgs DR. Mettananda S, et al. Ann N Y Acad Sci. 2016 Mar;1368(1):16-24. doi: 10.1111/nyas.12988. Epub 2015 Dec 22. Ann N Y Acad Sci. 2016. PMID: 26695885 Review.

4

Alternative Lengthening of Telomeres: Lessons to Be Learned from Telomeric DNA Double-Strand Break Repair.

Kent T, Clynes D. Kent T, et al. Genes (Basel). 2021 Oct 29;12(11):1734. doi: 10.3390/genes12111734. Genes (Basel). 2021. PMID: 34828344 Free PMC article. Review.

5

The chromatin remodeller ATRX facilitates diverse nuclear processes, in a stochastic manner, in both heterochromatin and euchromatin.

Truch J, Downes DJ, Scott C, Gür ER, Telenius JM, Repapi E, Schwessinger R, Gosden M, Brown JM, Taylor S, Cheong PL, Hughes JR, Higgs DR, Gibbons RJ. Truch J, et al. Nat Commun. 2022 Jun 17;13(1):3485. doi: 10.1038/s41467-022-31194-7. Nat Commun. 2022. PMID: 35710802 Free PMC article.

6

How to Tackle Challenging ChIP-Seq, with Long-Range Cross-Linking, Using ATRX as an Example.

Truch J, Telenius J, Higgs DR, Gibbons RJ. Truch J, et al. Methods Mol Biol. 2018;1832:105-130. doi: 10.1007/978-1-4939-8663-7_6. Methods Mol Biol. 2018. PMID: 30073524

7

ATRX Contributes to MeCP2-Mediated Pericentric Heterochromatin Organization during Neural Differentiation.

Marano D, Fioriniello S, Fiorillo F, Gibbons RJ, D'Esposito M, Della Ragione F. Marano D, et al. Int J Mol Sci. 2019 Oct 29;20(21):5371. doi: 10.3390/ijms20215371. Int J Mol Sci. 2019. PMID: 31671722 Free PMC article.

8

Variant ATRX syndrome with dysfunction of ATRX and MAGT1 genes.

Qiao Y, Mondal K, Trapani V, Wen J, Carpenter G, Wildin R, Price EM, Gibbons RJ, Eichmeyer J, Jiang R, DuPont B, Martell S, Lewis SM, Robinson WP, O'Driscoll M, Wolf FI, Zwick ME, Rajcan-Separovic E. Qiao Y, et al. Hum Mutat. 2014 Jan;35(1):58-62. doi: 10.1002/humu.22465. Hum Mutat. 2014. PMID: 24130152

9

Genetic dissection of the α-globin super-enhancer in vivo.

Hay D, Hughes JR, Babbs C, Davies JOJ, Graham BJ, Hanssen L, Kassouf MT, Marieke Oudelaar AM, Sharpe JA, Suciu MC, Telenius J, Williams R, Rode C, Li PS, Pennacchio LA, Sloane-Stanley JA, Ayyub H, Butler S, Sauka-Spengler T, Gibbons RJ, Smith AJH, Wood WG, Higgs DR. Hay D, et al. Nat Genet. 2016 Aug;48(8):895-903. doi: 10.1038/ng.3605. Epub 2016 Jul 4. Nat Genet. 2016. PMID: 27376235 Free PMC article.

10

The chromatin remodelling factor ATRX suppresses R-loops in transcribed telomeric repeats.

Nguyen DT, Voon HPJ, Xella B, Scott C, Clynes D, Babbs C, Ayyub H, Kerry J, Sharpe JA, Sloane-Stanley JA, Butler S, Fisher CA, Gray NE, Jenuwein T, Higgs DR, Gibbons RJ. Nguyen DT, et al. EMBO Rep. 2017 Jun;18(6):914-928. doi: 10.15252/embr.201643078. Epub 2017 May 9. EMBO Rep. 2017. PMID: 28487353 Free PMC article.

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