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Page 1
Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1.
Mills EL, Ryan DG, Prag HA, Dikovskaya D, Menon D, Zaslona Z, Jedrychowski MP, Costa ASH, Higgins M, Hams E, Szpyt J, Runtsch MC, King MS, McGouran JF, Fischer R, Kessler BM, McGettrick AF, Hughes MM, Carroll RG, Booty LM, Knatko EV, Meakin PJ, Ashford MLJ, Modis LK, Brunori G, Sévin DC, Fallon PG, Caldwell ST, Kunji ERS, Chouchani ET, Frezza C, Dinkova-Kostova AT, Hartley RC, Murphy MP, O'Neill LA. Mills EL, et al. Nature. 2018 Apr 5;556(7699):113-117. doi: 10.1038/nature25986. Epub 2018 Mar 28. Nature. 2018. PMID: 29590092 Free PMC article.
The transport mechanism of the mitochondrial ADP/ATP carrier.
Kunji ER, Aleksandrova A, King MS, Majd H, Ashton VL, Cerson E, Springett R, Kibalchenko M, Tavoulari S, Crichton PG, Ruprecht JJ. Kunji ER, et al. Biochim Biophys Acta. 2016 Oct;1863(10):2379-93. doi: 10.1016/j.bbamcr.2016.03.015. Epub 2016 Mar 19. Biochim Biophys Acta. 2016. PMID: 27001633 Free article. Review.
Mitochondrial pyruvate import and its effects on homeostasis.
Vanderperre B, Bender T, Kunji ER, Martinou JC. Vanderperre B, et al. Curr Opin Cell Biol. 2015 Apr;33:35-41. doi: 10.1016/j.ceb.2014.10.008. Epub 2014 Nov 15. Curr Opin Cell Biol. 2015. PMID: 25463844 Review.
Mitochondrial carriers function as monomers.
Kunji ER, Crichton PG. Kunji ER, et al. Biochim Biophys Acta. 2010 Jun-Jul;1797(6-7):817-31. doi: 10.1016/j.bbabio.2010.03.023. Epub 2010 Mar 31. Biochim Biophys Acta. 2010. PMID: 20362544 Free article. Review.
74 results