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2022 1
2023 2
2024 8

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Page 1
Tumour organoids and assembloids: Patient-derived cancer avatars for immunotherapy.
Mei J, Liu X, Tian HX, Chen Y, Cao Y, Zeng J, Liu YC, Chen Y, Gao Y, Yin JY, Wang PY. Mei J, et al. Clin Transl Med. 2024 Apr;14(4):e1656. doi: 10.1002/ctm2.1656. Clin Transl Med. 2024. PMID: 38664597 Free PMC article. Review.
Personalized drug screening has been practised; however, it remains unclear whether PDTOs can predict immunotherapies, including immune drugs (e.g. immune checkpoint inhibitors) and immune cells (e.g. tumour-infiltrating lymphocyte, T cell receptor-engineered T cell and chimeric …
Personalized drug screening has been practised; however, it remains unclear whether PDTOs can predict immunotherapies, including immune drug …
Immune characteristics associated with lymph node metastasis in early-stage NSCLC.
Zhang Z, Li L, Gao Y, Xiao X, Ji L, Zhou Z, Jiang J, Liu S, An J, Deng P, Du N, Li P, Xia X, Hu C, Li M. Zhang Z, et al. Cell Oncol (Dordr). 2024 Apr;47(2):447-461. doi: 10.1007/s13402-023-00873-y. Epub 2023 Sep 20. Cell Oncol (Dordr). 2024. PMID: 37728859
PURPOSE: Tumor metastasis significantly impacts the prognosis of non-small cell lung cancer (NSCLC) patients, with lymph node (LN) metastasis being the most common and early form of spread. ...METHODS: We showed the remodeled immune environment in TDLNs through usin …
PURPOSE: Tumor metastasis significantly impacts the prognosis of non-small cell lung cancer (NSCLC) patients, with lymph node …
Correlation between sarcopenia and esophageal cancer: a narrative review.
Li S, Xie K, Xiao X, Xu P, Tang M, Li D. Li S, et al. World J Surg Oncol. 2024 Jan 24;22(1):27. doi: 10.1186/s12957-024-03304-w. World J Surg Oncol. 2024. PMID: 38267975 Free PMC article. Review.
METHODS: A narrative review was performed in PubMed and Web of Science using the keywords ("esophageal cancer" or "esophageal neoplasm" or "neoplasm, esophageal" or "esophagus neoplasm" or "esophagus neoplasms" or "neoplasm, esophagus" or "neoplasms, esophagu …
METHODS: A narrative review was performed in PubMed and Web of Science using the keywords ("esophageal cancer" or "esophageal neoplas …
Circadian gene ARNTL initiates circGUCY1A2 transcription to suppress non-small cell lung cancer progression via miR-200c-3p/PTEN signaling.
Zhao D, Dong Y, Duan M, He D, Xie Q, Peng W, Cui W, Jiang J, Cheng Y, Zhang H, Tang F, Zhang C, Gao Y, Duan C. Zhao D, et al. J Exp Clin Cancer Res. 2023 Sep 4;42(1):229. doi: 10.1186/s13046-023-02791-1. J Exp Clin Cancer Res. 2023. PMID: 37667322 Free PMC article.
However, the functions and mechanisms by which circRNAs exert protective functions in non-small cell lung cancer (NSCLC) remain largely elusive. METHODS: The prognostic role of circGUCY1A2 was explored in lung adenocarcinoma specimens. ...RESULTS: The express …
However, the functions and mechanisms by which circRNAs exert protective functions in non-small cell lung cancer (NSCLC) remai …
Girdin Promotes Tumorigenesis and Chemoresistance in Lung Adenocarcinoma by Interacting with PKM2.
Cao F, Yang D, Tang F, Lu C, He X, Chen S, Yang Z, Gong S, Sun L, Enomoto A, Takahashi M, Weng L. Cao F, et al. Cancers (Basel). 2022 Nov 19;14(22):5688. doi: 10.3390/cancers14225688. Cancers (Basel). 2022. PMID: 36428781 Free PMC article.
However, the role of Girdin in a spontaneous tumor model has not yet been explored. Here, we studied the role of Girdin in lung adenocarcinoma (LUAD) using the autochthonous mouse model and found that Girdin led to LUAD progression and chemoresistance by enhancing the Warb …
However, the role of Girdin in a spontaneous tumor model has not yet been explored. Here, we studied the role of Girdin in lung adeno …
[Chinese expert consensus on refractory lung cancer].
Chinese Thoracic Society. Chinese Thoracic Society. Zhonghua Jie He He Hu Xi Za Zhi. 2024 Apr 12;47(4):301-312. doi: 10.3760/cma.j.cn112147-20231010-00215. Zhonghua Jie He He Hu Xi Za Zhi. 2024. PMID: 38599804 Chinese.
Refractory lung cancer is lung cancer that is unresponsive to standard treatment and is difficult to treat, or lung cancer for which a standard treatment has not yet been defined. ...It also provides references for Chinese clinicians on t …
Refractory lung cancer is lung cancer that is unresponsive to standard treatment and is difficult to treat, or …
The Causal Effect of Gut Microbiota and Plasma Metabolome on Lung Cancer and the Heterogeneity across Subtypes: A Mendelian Randomization Study.
Zeng J, Yi B, Chang R, Li J, Zhu J, Yu Z, Li X, Gao Y. Zeng J, et al. J Pers Med. 2024 Apr 25;14(5):453. doi: 10.3390/jpm14050453. J Pers Med. 2024. PMID: 38793035 Free PMC article.
The causal effect and pathways of gut microbiota and plasma metabolome on lung cancer have been important topics for personalized medicine; however, the heterogeneity of lung cancer subtypes has not gained enough attention in previous studies. . …
The causal effect and pathways of gut microbiota and plasma metabolome on lung cancer have been important topics for personali …
Optimal sequence of LT for symptomatic BM in EGFR-mutant NSCLC: a comparative study of first-line EGFR-TKIs with/without upfront LT.
Niu L, Wu H, Gao R, Chen L, Wang J, Duan H, Long Y, Xie Y, Zhou Q, Zhou R. Niu L, et al. J Cancer Res Clin Oncol. 2024 Feb 19;150(2):94. doi: 10.1007/s00432-023-05538-9. J Cancer Res Clin Oncol. 2024. PMID: 38369644 Free PMC article.
There is no consensus on the optimal sequence of local therapy (LT) and EGFR-TKIs for symptomatic BM patients because patients suffering neurological symptoms were not enrolled in most clinical trials. METHODS: Non-small cell lung cancer (NSCLC) patients with EGFR m …
There is no consensus on the optimal sequence of local therapy (LT) and EGFR-TKIs for symptomatic BM patients because patients suffering neu …
Effect of examining lymph nodes count on mortality risk in resected T1 non-small-cell lung cancer.
Zeng J, Liu Q, Chang R, Chen Y, Yu Z, Yi B, Gao Y. Zeng J, et al. Interdiscip Cardiovasc Thorac Surg. 2024 Feb 2;38(2):ivad195. doi: 10.1093/icvts/ivad195. Interdiscip Cardiovasc Thorac Surg. 2024. PMID: 38039183 Free PMC article.
OBJECTIVES: This study aims to estimate the effect of the examined lymph node count (ELNC) on the cancer-related mortality risk and non-cancer-related mortality risk in patients with resected T1 non-small-cell lung cancer (NSCLC). ...In competing risk …
OBJECTIVES: This study aims to estimate the effect of the examined lymph node count (ELNC) on the cancer-related mortality risk and n …
Prognostic and clinical significance of tumor-associated macrophages in esophageal squamous cell carcinoma after surgery: do biomarkers and distributions matter?
Yi B, Zeng J, Li L, Zhang J, Chen Y, Gao Y. Yi B, et al. Biosci Rep. 2024 Apr 24;44(4):BSR20231194. doi: 10.1042/BSR20231194. Biosci Rep. 2024. PMID: 38501293 Free PMC article.
RESULTS: Involving a total of 2,502 ESCC patients underwent surgery from 15 studies, the results suggested that the total count of CD68+ TAMs was inversely associated with OS and DFS in ESCC patients, which was also noticed in the relationship of CD68+ TAMs in tumor islet …
RESULTS: Involving a total of 2,502 ESCC patients underwent surgery from 15 studies, the results suggested that the total count of CD …