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The TLR3 signaling complex forms by cooperative receptor dimerization.
Leonard JN, Ghirlando R, Askins J, Bell JK, Margulies DH, Davies DR, Segal DM. Leonard JN, et al. Proc Natl Acad Sci U S A. 2008 Jan 8;105(1):258-63. doi: 10.1073/pnas.0710779105. Epub 2008 Jan 2. Proc Natl Acad Sci U S A. 2008. PMID: 18172197 Free PMC article.
Cisplatin enhances protein kinase R-like endoplasmic reticulum kinase- and CD95-dependent melanoma differentiation-associated gene-7/interleukin-24-induced killing in ovarian carcinoma cells.
Yacoub A, Liu R, Park MA, Hamed HA, Dash R, Schramm DN, Sarkar D, Dimitriev IP, Bell JK, Grant S, Farrell NP, Curiel DT, Fisher PB, Dent P. Yacoub A, et al. Mol Pharmacol. 2010 Feb;77(2):298-310. doi: 10.1124/mol.109.061820. Epub 2009 Nov 12. Mol Pharmacol. 2010. PMID: 19910452 Free PMC article.