K08 NS069625/NS/NINDS NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2010	1
2011	3
2014	1
2015	2
2016	1
2019	2
2020	1
2021	1
2022	1
2024	0

1

In vivo aggregation of presynaptic alpha-synuclein is not influenced by its phosphorylation at serine-129.

Weston LJ, Cook ZT, Stackhouse TL, Sal MK, Schultz BI, Tobias ZJC, Osterberg VR, Brockway NL, Pizano S, Glover G, Weissman TA, Unni VK. Weston LJ, et al. Neurobiol Dis. 2021 May;152:105291. doi: 10.1016/j.nbd.2021.105291. Epub 2021 Feb 5. Neurobiol Dis. 2021. PMID: 33556542 Free PMC article.

2

G2019S-LRRK2 Expression Augments α-Synuclein Sequestration into Inclusions in Neurons.

Volpicelli-Daley LA, Abdelmotilib H, Liu Z, Stoyka L, Daher JP, Milnerwood AJ, Unni VK, Hirst WD, Yue Z, Zhao HT, Fraser K, Kennedy RE, West AB. Volpicelli-Daley LA, et al. J Neurosci. 2016 Jul 13;36(28):7415-27. doi: 10.1523/JNEUROSCI.3642-15.2016. J Neurosci. 2016. PMID: 27413152 Free PMC article.

3

Curcumin Treatment Improves Motor Behavior in α-Synuclein Transgenic Mice.

Spinelli KJ, Osterberg VR, Meshul CK, Soumyanath A, Unni VK. Spinelli KJ, et al. PLoS One. 2015 Jun 2;10(6):e0128510. doi: 10.1371/journal.pone.0128510. eCollection 2015. PLoS One. 2015. PMID: 26035833 Free PMC article.

4

Aggregated Alpha-Synuclein Inclusions within the Nucleus Predict Impending Neuronal Cell Death in a Mouse Model of Parkinsonism.

Weston LJ, Bowman AM, Osterberg VR, Meshul CK, Woltjer RL, Unni VK. Weston LJ, et al. Int J Mol Sci. 2022 Dec 4;23(23):15294. doi: 10.3390/ijms232315294. Int J Mol Sci. 2022. PMID: 36499619 Free PMC article.

5

Multicolor lineage tracing using in vivo time-lapse imaging reveals coordinated death of clonally related cells in the developing vertebrate brain.

Brockway NL, Cook ZT, O'Gallagher MJ, Tobias ZJC, Gedi M, Carey KM, Unni VK, Pan YA, Metz MR, Weissman TA. Brockway NL, et al. Dev Biol. 2019 Sep 15;453(2):130-140. doi: 10.1016/j.ydbio.2019.05.006. Epub 2019 May 16. Dev Biol. 2019. PMID: 31102591 Free PMC article.

6

Presynaptic alpha-synuclein aggregation in a mouse model of Parkinson's disease.

Spinelli KJ, Taylor JK, Osterberg VR, Churchill MJ, Pollock E, Moore C, Meshul CK, Unni VK. Spinelli KJ, et al. J Neurosci. 2014 Feb 5;34(6):2037-50. doi: 10.1523/JNEUROSCI.2581-13.2014. J Neurosci. 2014. PMID: 24501346 Free PMC article.

7

Progressive aggregation of alpha-synuclein and selective degeneration of lewy inclusion-bearing neurons in a mouse model of parkinsonism.

Osterberg VR, Spinelli KJ, Weston LJ, Luk KC, Woltjer RL, Unni VK. Osterberg VR, et al. Cell Rep. 2015 Mar 3;10(8):1252-60. doi: 10.1016/j.celrep.2015.01.060. Epub 2015 Feb 26. Cell Rep. 2015. PMID: 25732816 Free PMC article.

8

Alpha-synuclein is a DNA binding protein that modulates DNA repair with implications for Lewy body disorders.

Schaser AJ, Osterberg VR, Dent SE, Stackhouse TL, Wakeham CM, Boutros SW, Weston LJ, Owen N, Weissman TA, Luna E, Raber J, Luk KC, McCullough AK, Woltjer RL, Unni VK. Schaser AJ, et al. Sci Rep. 2019 Jul 29;9(1):10919. doi: 10.1038/s41598-019-47227-z. Sci Rep. 2019. PMID: 31358782 Free PMC article.

9

Association of SNCA with Parkinson: replication in the Harvard NeuroDiscovery Center Biomarker Study.

Ding H, Sarokhan AK, Roderick SS, Bakshi R, Maher NE, Ashourian P, Kan CG, Chang S, Santarlasci A, Swords KE, Ravina BM, Hayes MT, Sohur US, Wills AM, Flaherty AW, Unni VK, Hung AY, Selkoe DJ, Schwarzschild MA, Schlossmacher MG, Sudarsky LR, Growdon JH, Ivinson AJ, Hyman BT, Scherzer CR. Ding H, et al. Mov Disord. 2011 Oct;26(12):2283-6. doi: 10.1002/mds.23934. Epub 2011 Sep 23. Mov Disord. 2011. PMID: 21953863 Free PMC article.

10

Distinct roles in vivo for the ubiquitin-proteasome system and the autophagy-lysosomal pathway in the degradation of α-synuclein.

Ebrahimi-Fakhari D, Cantuti-Castelvetri I, Fan Z, Rockenstein E, Masliah E, Hyman BT, McLean PJ, Unni VK. Ebrahimi-Fakhari D, et al. J Neurosci. 2011 Oct 12;31(41):14508-20. doi: 10.1523/JNEUROSCI.1560-11.2011. J Neurosci. 2011. PMID: 21994367 Free PMC article.

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