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A Polygenic Risk Score for Idiopathic Pulmonary Fibrosis and Interstitial Lung Abnormalities.
Moll M, Peljto AL, Kim JS, Xu H, Debban CL, Chen X, Menon A, Putman RK, Ghosh AJ, Saferali A, Nishino M, Hatabu H, Hobbs BD, Hecker J, McDermott G, Sparks JA, Wain LV, Allen RJ, Tobin MD, Raby BA, Chun S, Silverman EK, Zamora AC, Ortega VE, Garcia CK, Barr RG, Bleecker ER, Meyers DA, Kaner RJ, Rich SS, Manichaikul A, Rotter JI, Dupuis J, O'Connor GT, Fingerlin TE, Hunninghake GM, Schwartz DA, Cho MH. Moll M, et al. Am J Respir Crit Care Med. 2023 Oct 1;208(7):791-801. doi: 10.1164/rccm.202212-2257OC. Am J Respir Crit Care Med. 2023. PMID: 37523715
Polygenic risk scores identify heterogeneity in asthma and chronic obstructive pulmonary disease.
Moll M, Sordillo JE, Ghosh AJ, Hayden LP, McDermott G, McGeachie MJ, Dahlin A, Tiwari A, Manmadkar MG, Abston ED, Pavuluri C, Saferali A, Begum S, Ziniti JP, Gulsvik A, Bakke PS, Aschard H, Iribarren C, Hersh CP, Sparks JA, Hobbs BD, Lasky-Su JA, Silverman EK, Weiss ST, Wu AC, Cho MH. Moll M, et al. J Allergy Clin Immunol. 2023 Dec;152(6):1423-1432. doi: 10.1016/j.jaci.2023.08.002. Epub 2023 Aug 16. J Allergy Clin Immunol. 2023. PMID: 37595761
A polygenic risk score and age of diagnosis of COPD.
Zhang J, Xu H, Qiao D, DeMeo DL, Silverman EK, O'Connor GT, Hobbs BD, Dupuis J, Cho MH, Moll M. Zhang J, et al. Eur Respir J. 2022 Sep 15;60(3):2101954. doi: 10.1183/13993003.01954-2021. Print 2022 Sep. Eur Respir J. 2022. PMID: 35115341 Free PMC article.
Machine learning models for blood pressure phenotypes combining multiple polygenic risk scores.
Hrytsenko Y, Shea B, Elgart M, Kurniansyah N, Lyons G, Morrison AC, Carson AP, Haring B, Mitchel BD, Psaty BM, Jaeger BC, Gu CC, Kooperberg C, Levy D, Lloyd-Jones D, Choi E, Brody JA, Smith JA, Rotter JI, Moll M, Fornage M, Simon N, Castaldi P, Casanova R, Chung RH, Kaplan R, Loos RJF, Kardia SLR, Rich SS, Redline S, Kelly T, O'Connor T, Zhao W, Kim W, Guo X, Der Ida Chen Y; Trans-Omics in Precision Medicine Consortium; Sofer T. Hrytsenko Y, et al. medRxiv [Preprint]. 2023 Dec 14:2023.12.13.23299909. doi: 10.1101/2023.12.13.23299909. medRxiv. 2023. PMID: 38168328 Free PMC article. Preprint.
A robust and adaptive framework for interaction testing in quantitative traits between multiple genetic loci and exposure variables.
Hecker J, Prokopenko D, Moll M, Lee S, Kim W, Qiao D, Voorhies K, Kim W, Vansteelandt S, Hobbs BD, Cho MH, Silverman EK, Lutz SM, DeMeo DL, Weiss ST, Lange C. Hecker J, et al. PLoS Genet. 2022 Nov 16;18(11):e1010464. doi: 10.1371/journal.pgen.1010464. eCollection 2022 Nov. PLoS Genet. 2022. PMID: 36383614 Free PMC article.