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The oxylipin analog CS585 prevents platelet activation and thrombosis through activation of the prostacyclin receptor.
Blood. 2023 Nov 2;142(18):1556-1569. doi: 10.1182/blood.2023020622.
Blood. 2023.
PMID: 37624927
Experimental venous thrombus resolution is driven by IL-6 mediated monocyte actions.
Obi AT, Sharma SB, Elfline MA, Luke CE, Dowling AR, Cai Q, Kimball AS, Hollinstat M, Stanger L, Moore BB, Jaffer FA, Henke PK.
Obi AT, et al.
Sci Rep. 2023 Feb 24;13(1):3253. doi: 10.1038/s41598-023-30149-2.
Sci Rep. 2023.
PMID: 36828892
Free PMC article.
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The histone methyltransferase MLL1/KMT2A in monocytes drives coronavirus-associated coagulopathy and inflammation.
Sharma SB, Melvin WJ, Audu CO, Bame M, Rhoads N, Wu W, Kanthi Y, Knight JS, Adili R, Holinstat MA, Wakefield TW, Henke PK, Moore BB, Gallagher KA, Obi AT.
Sharma SB, et al.
Blood. 2023 Feb 16;141(7):725-742. doi: 10.1182/blood.2022015917.
Blood. 2023.
PMID: 36493338
Free PMC article.
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