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Regulation of FGF23: Beyond Bone.
Simic P, Babitt JL. Simic P, et al. Curr Osteoporos Rep. 2021 Dec;19(6):563-573. doi: 10.1007/s11914-021-00703-w. Epub 2021 Nov 10. Curr Osteoporos Rep. 2021. PMID: 34757587 Free PMC article. Review.
1,25-Dihydroxyvitamin D3 regulates furin-mediated FGF23 cleavage.
Xie H, Bastepe I, Zhou W, Ay B, Ceraj Z, Portales-Castillo IA, Liu ES, Burnett-Bowie SM, Jüppner H, Rhee EP, Bastepe M, Simic P. Xie H, et al. JCI Insight. 2023 Sep 8;8(17):e168957. doi: 10.1172/jci.insight.168957. JCI Insight. 2023. PMID: 37681408 Free PMC article.
Glycerol-3-phosphate is an FGF23 regulator derived from the injured kidney.
Simic P, Kim W, Zhou W, Pierce KA, Chang W, Sykes DB, Aziz NB, Elmariah S, Ngo D, Pajevic PD, Govea N, Kestenbaum BR, de Boer IH, Cheng Z, Christov M, Chun J, Leaf DE, Waikar SS, Tager AM, Gerszten RE, Thadhani RI, Clish CB, Jüppner H, Wein MN, Rhee EP. Simic P, et al. J Clin Invest. 2020 Mar 2;130(3):1513-1526. doi: 10.1172/JCI131190. J Clin Invest. 2020. PMID: 32065590 Free PMC article.