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Deletion of the nuclear localization sequence and C-terminus of parathyroid hormone-related protein decreases osteogenesis and chondrogenesis but increases adipogenesis and myogenesis in murine bone marrow stromal cells.
Hildreth BE 3rd, Hernon KM, Dirksen WP, Leong J, Supsavhad W, Boyaka PN, Rosol TJ, Toribio RE. Hildreth BE 3rd, et al. J Tissue Eng. 2015 Oct 12;6:2041731415609298. doi: 10.1177/2041731415609298. eCollection 2015 Jan-Dec. J Tissue Eng. 2015. PMID: 35003616 Free PMC article.
PTHrP 1-141 and 1-86 increase in vitro bone formation.
Hildreth BE 3rd, Werbeck JL, Thudi NK, Deng X, Rosol TJ, Toribio RE. Hildreth BE 3rd, et al. J Surg Res. 2010 Aug;162(2):e9-17. doi: 10.1016/j.jss.2010.02.023. Epub 2010 Mar 16. J Surg Res. 2010. PMID: 20538301 Free PMC article.