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2016 1
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2023 6
2024 0

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Page 1
Discovery of a 53BP1 Small Molecule Antagonist Using a Focused DNA-Encoded Library Screen.
Shell DJ, Foley CA, Wang Q, Smith CM, Guduru SKR, Zeng H, Dong A, Norris-Drouin JL, Axtman M, Hardy PB, Gupta G, Halabelian L, Frye SV, James LI, Pearce KH. Shell DJ, et al. Among authors: norris drouin jl. J Med Chem. 2023 Oct 26;66(20):14133-14149. doi: 10.1021/acs.jmedchem.3c01192. Epub 2023 Oct 2. J Med Chem. 2023. PMID: 37782247 Free PMC article.
Identification of Covalent Cyclic Peptide Inhibitors in mRNA Display.
Iskandar SE, Chiou LF, Leisner TM, Shell DJ, Norris-Drouin JL, Vaziri C, Pearce KH, Bowers AA. Iskandar SE, et al. Among authors: norris drouin jl. J Am Chem Soc. 2023 Jul 19;145(28):15065-15070. doi: 10.1021/jacs.3c04833. Epub 2023 Jul 3. J Am Chem Soc. 2023. PMID: 37395736
IRE1α Is a Therapeutic Target for Cystic Fibrosis Airway Inflammation.
Hull-Ryde EA, Minges JT, Martino MEB, Kato T, Norris-Drouin JL, Ribeiro CMP. Hull-Ryde EA, et al. Among authors: norris drouin jl. Int J Mol Sci. 2021 Mar 17;22(6):3063. doi: 10.3390/ijms22063063. Int J Mol Sci. 2021. PMID: 33802742 Free PMC article.
SETDB1 Triple Tudor Domain Ligand, (R,R)-59, Promotes Methylation of Akt1 in Cells.
Uguen M, Deng Y, Li F, Shell DJ, Norris-Drouin JL, Stashko MA, Ackloo S, Arrowsmith CH, James LI, Liu P, Pearce KH, Frye SV. Uguen M, et al. Among authors: norris drouin jl. ACS Chem Biol. 2023 Aug 18;18(8):1846-1853. doi: 10.1021/acschembio.3c00280. Epub 2023 Aug 9. ACS Chem Biol. 2023. PMID: 37556795 Free PMC article.
Discovery of hit compounds for methyl-lysine reader proteins from a target class DNA-encoded library.
Shell DJ, Rectenwald JM, Buttery PH, Johnson RL, Foley CA, Guduru SKR, Uguen M, Rubiano JS, Zhang X, Li F, Norris-Drouin JL, Axtman M, Brian Hardy P, Vedadi M, Frye SV, James LI, Pearce KH. Shell DJ, et al. Among authors: norris drouin jl. SLAS Discov. 2022 Dec;27(8):428-439. doi: 10.1016/j.slasd.2022.10.003. Epub 2022 Oct 19. SLAS Discov. 2022. PMID: 36272689 Free article.
21 results