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Year Number of Results
2018 1
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2020 9
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2022 6
2023 4
2024 0

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27 results

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Page 1
Effects of Human Milk Oligosaccharides on the Adult Gut Microbiota and Barrier Function.
Šuligoj T, Vigsnæs LK, Abbeele PVD, Apostolou A, Karalis K, Savva GM, McConnell B, Juge N. Šuligoj T, et al. Nutrients. 2020 Sep 13;12(9):2808. doi: 10.3390/nu12092808. Nutrients. 2020. PMID: 32933181 Free PMC article.
Here, we investigated the impact of HMOs on adult gut microbiota and gut barrier function using the Simulator of the Human Intestinal Microbial Ecosystem (SHIME()), Caco2 cell lines, and human intestinal gut organoid-on-chips. ...Taken together, these data sh …
Here, we investigated the impact of HMOs on adult gut microbiota and gut barrier function using the Simulator of the Human Int …
Serine-rich repeat proteins from gut microbes.
Latousakis D, MacKenzie DA, Telatin A, Juge N. Latousakis D, et al. Gut Microbes. 2020;11(1):102-117. doi: 10.1080/19490976.2019.1602428. Epub 2019 Apr 29. Gut Microbes. 2020. PMID: 31035824 Free PMC article. Review.
Recently, the non-canonical aSec system has been identified in the genomes of gut microbes and characterization of their associated SRRPs is beginning to unfold, showing their role in mediating attachment and biofilm formation. Here we provide an update of the occur …
Recently, the non-canonical aSec system has been identified in the genomes of gut microbes and characterization of their assoc …
Relationship between mucosa-associated gut microbiota and human diseases.
Juge N. Juge N. Biochem Soc Trans. 2022 Oct 31;50(5):1225-1236. doi: 10.1042/BST20201201. Biochem Soc Trans. 2022. PMID: 36214382 Free PMC article. Review.
The mucus layer covering the gastrointestinal (GI) tract plays a critical role in maintaining gut homeostasis. In the colon, the inner mucus layer ensures commensal microbes are kept at a safe distance from the epithelium while mucin glycans in the outer mucus layer …
The mucus layer covering the gastrointestinal (GI) tract plays a critical role in maintaining gut homeostasis. In the colon, the inne …
Biochemical and structural basis of sialic acid utilization by gut microbes.
Bell A, Severi E, Owen CD, Latousakis D, Juge N. Bell A, et al. J Biol Chem. 2023 Mar;299(3):102989. doi: 10.1016/j.jbc.2023.102989. Epub 2023 Feb 8. J Biol Chem. 2023. PMID: 36758803 Free PMC article. Review.
The repartition and availability of sialic acid derivatives in the gut have a significant impact on the modulation of gut microbes and host susceptibility to infection and inflammation. ...In this review, we provide an update on the mechanisms underpinning si …
The repartition and availability of sialic acid derivatives in the gut have a significant impact on the modulation of gut m
Mucosal glycan degradation of the host by the gut microbiota.
Bell A, Juge N. Bell A, et al. Glycobiology. 2021 Jun 29;31(6):691-696. doi: 10.1093/glycob/cwaa097. Glycobiology. 2021. PMID: 33043970 Free PMC article. Review.
The gut microbiota plays a major role in human health and an alteration in gut microbiota structure and function has been implicated in several diseases. ...Access to these glycan chains requires a complement of glycoside hydrolases (GHs) produced by bacteria …
The gut microbiota plays a major role in human health and an alteration in gut microbiota structure and function has be …
The Role of the Microbiome in Liver Cancer.
Moreno-Gonzalez M, Beraza N. Moreno-Gonzalez M, et al. Cancers (Basel). 2021 May 12;13(10):2330. doi: 10.3390/cancers13102330. Cancers (Basel). 2021. PMID: 34066064 Free PMC article. Review.
Structure and function of microbial α-l-fucosidases: a mini review.
Wu H, Owen CD, Juge N. Wu H, et al. Essays Biochem. 2023 Apr 18;67(3):399-414. doi: 10.1042/EBC20220158. Essays Biochem. 2023. PMID: 36805644 Free PMC article. Review.
.-) have been reported in the GH29, GH95, GH139, GH141 and GH151 families of the Carbohydrate Active Enzymes (CAZy) database. Microbes generally encode several fucosidases in their genomes, often from more than one GH family, reflecting the high diversity of naturally occu …
.-) have been reported in the GH29, GH95, GH139, GH141 and GH151 families of the Carbohydrate Active Enzymes (CAZy) database. Microbes
Fucosidases from the human gut symbiont Ruminococcus gnavus.
Wu H, Rebello O, Crost EH, Owen CD, Walpole S, Bennati-Granier C, Ndeh D, Monaco S, Hicks T, Colvile A, Urbanowicz PA, Walsh MA, Angulo J, Spencer DIR, Juge N. Wu H, et al. Cell Mol Life Sci. 2021 Jan;78(2):675-693. doi: 10.1007/s00018-020-03514-x. Epub 2020 Apr 24. Cell Mol Life Sci. 2021. PMID: 32333083 Free PMC article.
The availability and repartition of fucosylated glycans within the gastrointestinal tract contributes to the adaptation of gut bacteria species to ecological niches. To access this source of nutrients, gut bacteria encode alpha-L-fucosidases (fucosidases) which cata …
The availability and repartition of fucosylated glycans within the gastrointestinal tract contributes to the adaptation of gut bacter …
Role of mucin glycosylation in the gut microbiota-brain axis of core 3 O-glycan deficient mice.
Coletto E, Savva GM, Latousakis D, Pontifex M, Crost EH, Vaux L, Telatin A, Bergstrom K, Vauzour D, Juge N. Coletto E, et al. Sci Rep. 2023 Aug 26;13(1):13982. doi: 10.1038/s41598-023-40497-8. Sci Rep. 2023. PMID: 37634035 Free PMC article.
Here, we used mice lacking core 3-derived O-glycans (C3GnT(-/-)) to investigate the effect of impaired mucin glycosylation in the gut-brain axis. C3GnT(-/-) mice showed altered microbial metabolites in the caecum associated with brain function such as dimethylglycine and N …
Here, we used mice lacking core 3-derived O-glycans (C3GnT(-/-)) to investigate the effect of impaired mucin glycosylation in the gut
27 results