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The first Chinese national standards for SARS-CoV-2 neutralizing antibody.
Guan L, Yu Y, Wu X, Nie J, Zhang J, Wang Z, Li N, Shi R, Zhao H, Chen H, Luo C, Hu Y, Wang Y, Huang W, Xu M, Hou J. Guan L, et al. Vaccine. 2021 Jun 23;39(28):3724-3730. doi: 10.1016/j.vaccine.2021.05.047. Epub 2021 May 19. Vaccine. 2021. PMID: 34059373 Free PMC article.
A second functional furin site in the SARS-CoV-2 spike protein.
Zhang Y, Zhang L, Wu J, Yu Y, Liu S, Li T, Li Q, Ding R, Wang H, Nie J, Cui Z, Wang Y, Huang W, Wang Y. Zhang Y, et al. Emerg Microbes Infect. 2022 Dec;11(1):182-194. doi: 10.1080/22221751.2021.2014284. Emerg Microbes Infect. 2022. PMID: 34856891 Free PMC article.
SARS-CoV-2 501Y.V2 variants lack higher infectivity but do have immune escape.
Li Q, Nie J, Wu J, Zhang L, Ding R, Wang H, Zhang Y, Li T, Liu S, Zhang M, Zhao C, Liu H, Nie L, Qin H, Wang M, Lu Q, Li X, Liu J, Liang H, Shi Y, Shen Y, Xie L, Zhang L, Qu X, Xu W, Huang W, Wang Y. Li Q, et al. Cell. 2021 Apr 29;184(9):2362-2371.e9. doi: 10.1016/j.cell.2021.02.042. Epub 2021 Feb 23. Cell. 2021. PMID: 33735608 Free PMC article.
The antigenicity of SARS-CoV-2 Delta variants aggregated 10 high-frequency mutations in RBD has not changed sufficiently to replace the current vaccine strain.
Wu J, Nie J, Zhang L, Song H, An Y, Liang Z, Yang J, Ding R, Liu S, Li Q, Li T, Cui Z, Zhang M, He P, Wang Y, Qu X, Hu Z, Wang Q, Huang W. Wu J, et al. Signal Transduct Target Ther. 2022 Jan 19;7(1):18. doi: 10.1038/s41392-022-00874-7. Signal Transduct Target Ther. 2022. PMID: 35046385 Free PMC article.
11 results