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2012 1
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Page 1
Synthesis of Deuterated Endochin-Like Quinolones.
Pou S, Winter RW, Liebman KM, Dodean RA, Nilsen A, DeBarber A, Doggett JS, Riscoe MK. Pou S, et al. J Labelled Comp Radiopharm. 2024 May 15;67(5):186-196. doi: 10.1002/jlcr.4092. Epub 2024 Apr 25. J Labelled Comp Radiopharm. 2024. PMID: 38661253
Robenidine derivatives as potential antischistosomal drug candidates.
Lotz CN, Krollenbrock A, Imhof L, Riscoe M, Keiser J. Lotz CN, et al. Int J Parasitol Drugs Drug Resist. 2024 May 5;25:100546. doi: 10.1016/j.ijpddr.2024.100546. Online ahead of print. Int J Parasitol Drugs Drug Resist. 2024. PMID: 38733883 Free PMC article.
Targeted Structure-Activity Analysis of Endochin-like Quinolones Reveals Potent Qi and Qo Site Inhibitors of Toxoplasma gondii and Plasmodium falciparum Cytochrome bc1 and Identifies ELQ-400 as a Remarkably Effective Compound against Acute Experimental Toxoplasmosis.
McConnell EV, Bruzual I, Pou S, Winter R, Dodean RA, Smilkstein MJ, Krollenbrock A, Nilsen A, Zakharov LN, Riscoe MK, Doggett JS. McConnell EV, et al. ACS Infect Dis. 2018 Nov 9;4(11):1574-1584. doi: 10.1021/acsinfecdis.8b00133. Epub 2018 Aug 30. ACS Infect Dis. 2018. PMID: 30117728 Free PMC article.
Discovery, synthesis, and optimization of antimalarial 4(1H)-quinolone-3-diarylethers.
Nilsen A, Miley GP, Forquer IP, Mather MW, Katneni K, Li Y, Pou S, Pershing AM, Stickles AM, Ryan E, Kelly JX, Doggett JS, White KL, Hinrichs DJ, Winter RW, Charman SA, Zakharov LN, Bathurst I, Burrows JN, Vaidya AB, Riscoe MK. Nilsen A, et al. J Med Chem. 2014 May 8;57(9):3818-34. doi: 10.1021/jm500147k. Epub 2014 Apr 18. J Med Chem. 2014. PMID: 24720377 Free PMC article.
A New Scalable Synthesis of ELQ-300, ELQ-316, and other Antiparasitic Quinolones.
Pou S, Dodean RA, Frueh L, Liebman KM, Gallagher RT, Jin H, Jacobs RT, Nilsen A, Stuart DR, Doggett JS, Riscoe MK, Winter RW. Pou S, et al. Org Process Res Dev. 2021 Aug 20;25(8):1841-1852. doi: 10.1021/acs.oprd.1c00099. Epub 2021 Aug 4. Org Process Res Dev. 2021. PMID: 35110959 Free PMC article.
30 results