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FTY720 and (S)-FTY720 vinylphosphonate inhibit sphingosine kinase 1 and promote its proteasomal degradation in human pulmonary artery smooth muscle, breast cancer and androgen-independent prostate cancer cells.
Tonelli F, Lim KG, Loveridge C, Long J, Pitson SM, Tigyi G, Bittman R, Pyne S, Pyne NJ. Tonelli F, et al. Cell Signal. 2010 Oct;22(10):1536-42. doi: 10.1016/j.cellsig.2010.05.022. Epub 2010 Jun 4. Cell Signal. 2010. PMID: 20570726 Free PMC article.
Plasma gelsolin modulates cellular response to sphingosine 1-phosphate.
Bucki R, Kulakowska A, Byfield FJ, Zendzian-Piotrowska M, Baranowski M, Marzec M, Winer JP, Ciccarelli NJ, Górski J, Drozdowski W, Bittman R, Janmey PA. Bucki R, et al. Am J Physiol Cell Physiol. 2010 Dec;299(6):C1516-23. doi: 10.1152/ajpcell.00051.2010. Epub 2010 Sep 1. Am J Physiol Cell Physiol. 2010. PMID: 20810916 Free PMC article.
45 results