FS/14/30/30917/BHF_/British Heart Foundation/United Kingdom[Grants and Funding] - Search Results

Year	Number of Results
2015	1
2018	3
2019	4
2020	2
2022	2
2024	0

1

Mix and (mis-)match - The mechanosensing machinery in the changing environment of the developing, healthy adult and diseased heart.

Ward M, Iskratsch T. Ward M, et al. Biochim Biophys Acta Mol Cell Res. 2020 Mar;1867(3):118436. doi: 10.1016/j.bbamcr.2019.01.017. Epub 2019 Feb 8. Biochim Biophys Acta Mol Cell Res. 2020. PMID: 30742931 Free PMC article. Review.

2

Cardiomyocytes Sense Matrix Rigidity through a Combination of Muscle and Non-muscle Myosin Contractions.

Pandey P, Hawkes W, Hu J, Megone WV, Gautrot J, Anilkumar N, Zhang M, Hirvonen L, Cox S, Ehler E, Hone J, Sheetz M, Iskratsch T. Pandey P, et al. Dev Cell. 2018 Feb 5;44(3):326-336.e3. doi: 10.1016/j.devcel.2017.12.024. Epub 2018 Jan 26. Dev Cell. 2018. PMID: 29396114 Free PMC article.

3

Pressure and stiffness sensing together regulate vascular smooth muscle cell phenotype switching.

Swiatlowska P, Sit B, Feng Z, Marhuenda E, Xanthis I, Zingaro S, Ward M, Zhou X, Xiao Q, Shanahan C, Jones GE, Yu CH, Iskratsch T. Swiatlowska P, et al. Sci Adv. 2022 Apr 15;8(15):eabm3471. doi: 10.1126/sciadv.abm3471. Epub 2022 Apr 15. Sci Adv. 2022. PMID: 35427166 Free PMC article.

4

Regulation of cardiomyocyte adhesion and mechanosignalling through distinct nanoscale behaviour of integrin ligands mimicking healthy or fibrotic extracellular matrix.

Hawkes W, Marhuenda E, Reynolds P, O'Neill C, Pandey P, Samuel Wilson DG, Freeley M, Huang D, Hu J, Gondarenko S, Hone J, Gadegaard N, Palma M, Iskratsch T. Hawkes W, et al. Philos Trans R Soc Lond B Biol Sci. 2022 Nov 21;377(1864):20220021. doi: 10.1098/rstb.2022.0021. Epub 2022 Oct 3. Philos Trans R Soc Lond B Biol Sci. 2022. PMID: 36189804 Free PMC article.

5

Calponin-3 is critical for coordinated contractility of actin stress fibers.

Ciuba K, Hawkes W, Tojkander S, Kogan K, Engel U, Iskratsch T, Lappalainen P. Ciuba K, et al. Sci Rep. 2018 Dec 5;8(1):17670. doi: 10.1038/s41598-018-35948-6. Sci Rep. 2018. PMID: 30518778 Free PMC article.

6

Contractile myosin rings and cofilin-mediated actin disassembly orchestrate ECM nanotopography sensing.

Di Cio S, Iskratsch T, Connelly JT, Gautrot JE. Di Cio S, et al. Biomaterials. 2020 Feb;232:119683. doi: 10.1016/j.biomaterials.2019.119683. Epub 2019 Dec 16. Biomaterials. 2020. PMID: 31927180 Free article.

7

Probing the nanoscale organisation and multivalency of cell surface receptors: DNA origami nanoarrays for cellular studies with single-molecule control.

Hawkes W, Huang D, Reynolds P, Hammond L, Ward M, Gadegaard N, Marshall JF, Iskratsch T, Palma M. Hawkes W, et al. Faraday Discuss. 2019 Oct 30;219(0):203-219. doi: 10.1039/c9fd00023b. Faraday Discuss. 2019. PMID: 31314021 Free article.

8

Micropatterning of TCR and LFA-1 ligands reveals complementary effects on cytoskeleton mechanics in T cells.

Tabdanov E, Gondarenko S, Kumari S, Liapis A, Dustin ML, Sheetz MP, Kam LC, Iskratsch T. Tabdanov E, et al. Integr Biol (Camb). 2015 Oct;7(10):1272-84. doi: 10.1039/c5ib00032g. Epub 2015 Jul 9. Integr Biol (Camb). 2015. PMID: 26156536 Free PMC article.

9

Cardiomyocytes Sense Matrix Rigidity through a Combination of Muscle and Non-muscle Myosin Contractions.

Pandey P, Hawkes W, Hu J, Megone WV, Gautrot J, Anilkumar N, Zhang M, Hirvonen L, Cox S, Ehler E, Hone J, Sheetz M, Iskratsch T. Pandey P, et al. Dev Cell. 2018 Jun 4;45(5):661. doi: 10.1016/j.devcel.2018.05.016. Dev Cell. 2018. PMID: 29870723 Free PMC article. No abstract available.

10

Tumor Angiogenesis Is Differentially Regulated by Phosphorylation of Endothelial Cell Focal Adhesion Kinase Tyrosines-397 and -861.

Pedrosa AR, Bodrug N, Gomez-Escudero J, Carter EP, Reynolds LE, Georgiou PN, Fernandez I, Lees DM, Kostourou V, Alexopoulou AN, Batista S, Tavora B, Serrels B, Parsons M, Iskratsch T, Hodivala-Dilke KM. Pedrosa AR, et al. Cancer Res. 2019 Sep 1;79(17):4371-4386. doi: 10.1158/0008-5472.CAN-18-3934. Epub 2019 Jun 12. Cancer Res. 2019. PMID: 31189647

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