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Ceramide mediates vascular dysfunction in diet-induced obesity by PP2A-mediated dephosphorylation of the eNOS-Akt complex.
Zhang QJ, Holland WL, Wilson L, Tanner JM, Kearns D, Cahoon JM, Pettey D, Losee J, Duncan B, Gale D, Kowalski CA, Deeter N, Nichols A, Deesing M, Arrant C, Ruan T, Boehme C, McCamey DR, Rou J, Ambal K, Narra KK, Summers SA, Abel ED, Symons JD. Zhang QJ, et al. Diabetes. 2012 Jul;61(7):1848-59. doi: 10.2337/db11-1399. Epub 2012 May 14. Diabetes. 2012. PMID: 22586587 Free PMC article.
The ceramide ratio: a predictor of cardiometabolic risk.
Tippetts TS, Holland WL, Summers SA. Tippetts TS, et al. J Lipid Res. 2018 Sep;59(9):1549-1550. doi: 10.1194/jlr.C088377. Epub 2018 Jul 9. J Lipid Res. 2018. PMID: 29987126 Free PMC article. No abstract available.