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Year | Number of Results |
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2015 | 3 |
2016 | 1 |
2017 | 1 |
2019 | 1 |
2024 | 0 |
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6 results
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Page 1
Structure-Activity Relationship for the 4(3H)-Quinazolinone Antibacterials.
J Med Chem. 2016 May 26;59(10):5011-21. doi: 10.1021/acs.jmedchem.6b00372. Epub 2016 May 5.
J Med Chem. 2016.
PMID: 27088777
Free PMC article.
Discovery of antibiotic (E)-3-(3-carboxyphenyl)-2-(4-cyanostyryl)quinazolin-4(3H)-one.
Bouley R, Kumarasiri M, Peng Z, Otero LH, Song W, Suckow MA, Schroeder VA, Wolter WR, Lastochkin E, Antunes NT, Pi H, Vakulenko S, Hermoso JA, Chang M, Mobashery S.
Bouley R, et al.
J Am Chem Soc. 2015 Feb 11;137(5):1738-41. doi: 10.1021/jacs.5b00056. Epub 2015 Feb 2.
J Am Chem Soc. 2015.
PMID: 25629446
Free PMC article.
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Synergistic, collaterally sensitive β-lactam combinations suppress resistance in MRSA.
Gonzales PR, Pesesky MW, Bouley R, Ballard A, Biddy BA, Suckow MA, Wolter WR, Schroeder VA, Burnham CA, Mobashery S, Chang M, Dantas G.
Gonzales PR, et al.
Nat Chem Biol. 2015 Nov;11(11):855-61. doi: 10.1038/nchembio.1911. Epub 2015 Sep 14.
Nat Chem Biol. 2015.
PMID: 26368589
Free PMC article.
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Synthesis and evaluation of 1,2,4-triazolo[1,5-a]pyrimidines as antibacterial agents against Enterococcus faecium.
Wang H, Lee M, Peng Z, Blázquez B, Lastochkin E, Kumarasiri M, Bouley R, Chang M, Mobashery S.
Wang H, et al.
J Med Chem. 2015 May 28;58(10):4194-203. doi: 10.1021/jm501831g. Epub 2015 May 12.
J Med Chem. 2015.
PMID: 25923368
Free PMC article.
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The Quinazolinone Allosteric Inhibitor of PBP 2a Synergizes with Piperacillin and Tazobactam against Methicillin-Resistant Staphylococcus aureus.
Janardhanan J, Bouley R, Martínez-Caballero S, Peng Z, Batuecas-Mordillo M, Meisel JE, Ding D, Schroeder VA, Wolter WR, Mahasenan KV, Hermoso JA, Mobashery S, Chang M.
Janardhanan J, et al.
Antimicrob Agents Chemother. 2019 Apr 25;63(5):e02637-18. doi: 10.1128/AAC.02637-18. Print 2019 May.
Antimicrob Agents Chemother. 2019.
PMID: 30858202
Free PMC article.
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Conformational Dynamics in Penicillin-Binding Protein 2a of Methicillin-Resistant Staphylococcus aureus, Allosteric Communication Network and Enablement of Catalysis.
Mahasenan KV, Molina R, Bouley R, Batuecas MT, Fisher JF, Hermoso JA, Chang M, Mobashery S.
Mahasenan KV, et al.
J Am Chem Soc. 2017 Feb 8;139(5):2102-2110. doi: 10.1021/jacs.6b12565. Epub 2017 Jan 27.
J Am Chem Soc. 2017.
PMID: 28099001
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