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Serotonin engages an anxiety and fear-promoting circuit in the extended amygdala.
Marcinkiewcz CA, Mazzone CM, D'Agostino G, Halladay LR, Hardaway JA, DiBerto JF, Navarro M, Burnham N, Cristiano C, Dorrier CE, Tipton GJ, Ramakrishnan C, Kozicz T, Deisseroth K, Thiele TE, McElligott ZA, Holmes A, Heisler LK, Kash TL. Marcinkiewcz CA, et al. Nature. 2016 Sep 1;537(7618):97-101. doi: 10.1038/nature19318. Epub 2016 Aug 24. Nature. 2016. PMID: 27556938 Free PMC article.
Central Amygdala Prepronociceptin-Expressing Neurons Mediate Palatable Food Consumption and Reward.
Hardaway JA, Halladay LR, Mazzone CM, Pati D, Bloodgood DW, Kim M, Jensen J, DiBerto JF, Boyt KM, Shiddapur A, Erfani A, Hon OJ, Neira S, Stanhope CM, Sugam JA, Saddoris MP, Tipton G, McElligott Z, Jhou TC, Stuber GD, Bruchas MR, Bulik CM, Holmes A, Kash TL. Hardaway JA, et al. Neuron. 2019 Jun 5;102(5):1037-1052.e7. doi: 10.1016/j.neuron.2019.03.037. Epub 2019 Apr 24. Neuron. 2019. PMID: 31029403 Free PMC article.
Nociceptin receptor antagonist SB 612111 decreases high fat diet binge eating.
Hardaway JA, Jensen J, Kim M, Mazzone CM, Sugam JA, Diberto JF, Lowery-Gionta EG, Hwa LS, Pleil KE, Bulik CM, Kash TL. Hardaway JA, et al. Behav Brain Res. 2016 Jul 1;307:25-34. doi: 10.1016/j.bbr.2016.03.046. Epub 2016 Mar 29. Behav Brain Res. 2016. PMID: 27036650 Free PMC article.