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Year | Number of Results |
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Novel Murine Models of Cerebral Cavernous Malformations.
Angiogenesis. 2020 Nov;23(4):651-666. doi: 10.1007/s10456-020-09736-8. Epub 2020 Jul 24.
Angiogenesis. 2020.
PMID: 32710309
Free PMC article.
Propranolol as therapy for cerebral cavernous malformations: a cautionary note.
Shenkar R, Moore T, Benavides C, Lightle R, Detter MR, Hobson N, Girard R, DeBiasse D, Patrucco M, Gallione C, Zabramski JM, Marchuk DA, Awad IA.
Shenkar R, et al.
J Transl Med. 2022 Apr 5;20(1):160. doi: 10.1186/s12967-022-03360-4.
J Transl Med. 2022.
PMID: 35382850
Free PMC article.
No abstract available.
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Transcriptome clarifies mechanisms of lesion genesis versus progression in models of Ccm3 cerebral cavernous malformations.
Koskimäki J, Zhang D, Li Y, Saadat L, Moore T, Lightle R, Polster SP, Carrión-Penagos J, Lyne SB, Zeineddine HA, Shi C, Shenkar R, Romanos S, Avner K, Srinath A, Shen L, Detter MR, Snellings D, Cao Y, Lopez-Ramirez MA, Fonseca G, Tang AT, Faber P, Andrade J, Ginsberg M, Kahn ML, Marchuk DA, Girard R, Awad IA.
Koskimäki J, et al.
Acta Neuropathol Commun. 2019 Aug 19;7(1):132. doi: 10.1186/s40478-019-0789-0.
Acta Neuropathol Commun. 2019.
PMID: 31426861
Free PMC article.
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Cerebral cavernous malformations are driven by ADAMTS5 proteolysis of versican.
Hong CC, Tang AT, Detter MR, Choi JP, Wang R, Yang X, Guerrero AA, Wittig CF, Hobson N, Girard R, Lightle R, Moore T, Shenkar R, Polster SP, Goddard LM, Ren AA, Leu NA, Sterling S, Yang J, Li L, Chen M, Mericko-Ishizuka P, Dow LE, Watanabe H, Schwaninger M, Min W, Marchuk DA, Zheng X, Awad IA, Kahn ML.
Hong CC, et al.
J Exp Med. 2020 Oct 5;217(10):e20200140. doi: 10.1084/jem.20200140.
J Exp Med. 2020.
PMID: 32648916
Free PMC article.
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Propranolol inhibits cavernous vascular malformations by β1 adrenergic receptor antagonism in animal models.
Li W, Shenkar R, Detter MR, Moore T, Benavides C, Lightle R, Girard R, Hobson N, Cao Y, Li Y, Griffin E, Gallione C, Zabramski JM, Ginsberg MH, Marchuk DA, Awad IA.
Li W, et al.
J Clin Invest. 2021 Feb 1;131(3):e144893. doi: 10.1172/JCI144893.
J Clin Invest. 2021.
PMID: 33301422
Free PMC article.
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Cerebral Cavernous Malformations Develop Through Clonal Expansion of Mutant Endothelial Cells.
Detter MR, Snellings DA, Marchuk DA.
Detter MR, et al.
Circ Res. 2018 Oct 26;123(10):1143-1151. doi: 10.1161/CIRCRESAHA.118.313970.
Circ Res. 2018.
PMID: 30359189
Free PMC article.
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Propranolol inhibits cavernous vascular malformations by β1 adrenergic receptor antagonism in animal models.
Li W, Shenkar R, Detter MR, Moore T, Benavides C, Lightle R, Girard R, Hobson N, Cao Y, Li Y, Griffin E, Gallione C, Zabramski JM, Ginsberg MH, Marchuk DA, Awad IA.
Li W, et al.
J Clin Invest. 2021 Oct 1;131(19):e154909. doi: 10.1172/JCI154909.
J Clin Invest. 2021.
PMID: 34596055
Free PMC article.
No abstract available.
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