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Rapid morphologic changes to microglial cells and upregulation of mixed microglial activation state markers induced by P2X7 receptor stimulation and increased intraocular pressure.
J Neuroinflammation. 2021 Sep 20;18(1):217. doi: 10.1186/s12974-021-02251-7.
J Neuroinflammation. 2021.
PMID: 34544431
Free PMC article.
Stimulation of P2X7 receptors elevates Ca2+ and kills retinal ganglion cells.
Zhang X, Zhang M, Laties AM, Mitchell CH.
Zhang X, et al.
Invest Ophthalmol Vis Sci. 2005 Jun;46(6):2183-91. doi: 10.1167/iovs.05-0052.
Invest Ophthalmol Vis Sci. 2005.
PMID: 15914640
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Balance of purines may determine life or death of retinal ganglion cells as A3 adenosine receptors prevent loss following P2X7 receptor stimulation.
Zhang X, Zhang M, Laties AM, Mitchell CH.
Zhang X, et al.
J Neurochem. 2006 Jul;98(2):566-75. doi: 10.1111/j.1471-4159.2006.03900.x.
J Neurochem. 2006.
PMID: 16805847
Free article.
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Restoration of lysosomal pH in RPE cells from cultured human and ABCA4(-/-) mice: pharmacologic approaches and functional recovery.
Liu J, Lu W, Reigada D, Nguyen J, Laties AM, Mitchell CH.
Liu J, et al.
Invest Ophthalmol Vis Sci. 2008 Feb;49(2):772-80. doi: 10.1167/iovs.07-0675.
Invest Ophthalmol Vis Sci. 2008.
PMID: 18235027
Free PMC article.
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Sustained elevation of extracellular ATP in aqueous humor from humans with primary chronic angle-closure glaucoma.
Li A, Zhang X, Zheng D, Ge J, Laties AM, Mitchell CH.
Li A, et al.
Exp Eye Res. 2011 Oct;93(4):528-33. doi: 10.1016/j.exer.2011.06.020. Epub 2011 Jul 2.
Exp Eye Res. 2011.
PMID: 21745471
Free PMC article.
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Cystic fibrosis transmembrane conductance regulator contributes to reacidification of alkalinized lysosomes in RPE cells.
Liu J, Lu W, Guha S, Baltazar GC, Coffey EE, Laties AM, Rubenstein RC, Reenstra WW, Mitchell CH.
Liu J, et al.
Am J Physiol Cell Physiol. 2012 Jul 15;303(2):C160-9. doi: 10.1152/ajpcell.00278.2011. Epub 2012 May 9.
Am J Physiol Cell Physiol. 2012.
PMID: 22572847
Free PMC article.
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