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Nonenzymatically oxidized arachidonic acid regulates T-type Ca2+ currents in mouse spermatogenic cells.
Bondarenko O, Corzo G, Santana FL, Del Río-Portilla F, Darszon A, López-González I. Bondarenko O, et al. FEBS Lett. 2019 Jul;593(14):1735-1750. doi: 10.1002/1873-3468.13448. Epub 2019 Jun 6. FEBS Lett. 2019. PMID: 31115913 Free article.
The spontaneous oxidation of fatty acids causes a decrease in mammalian fertility. Here, we examine the effects of nonenzymatically oxidized arachidonic acid (AA(ox) ) on mouse spermatogenic T-type Ca(2+) currents (I(CaT) ) due to their physiological relevance during sperm …
The spontaneous oxidation of fatty acids causes a decrease in mammalian fertility. Here, we examine the effects of nonenzymatically o …
Novel Alligator Cathelicidin As-CATH8 Demonstrates Anti-Infective Activity against Clinically Relevant and Crocodylian Bacterial Pathogens.
Santana FL, Estrada K, Alford MA, Wu BC, Dostert M, Pedraz L, Akhoundsadegh N, Kalsi P, Haney EF, Straus SK, Corzo G, Hancock REW. Santana FL, et al. Antibiotics (Basel). 2022 Nov 11;11(11):1603. doi: 10.3390/antibiotics11111603. Antibiotics (Basel). 2022. PMID: 36421248 Free PMC article.
As-CATH8 displayed greater antibiofilm activity than the human cathelicidin LL-37 against methicillin-resistant Staphylococcus aureus in a human organoid model of biofilm skin infection. Furthermore, As-CATH8 demonstrated strong antibacterial effects in a murine abscess mo …
As-CATH8 displayed greater antibiofilm activity than the human cathelicidin LL-37 against methicillin-resistant Staphylococcus aureus in a h …