DP2 OD008459/OD/NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2012	2
2014	1
2015	5
2016	6
2017	7
2019	1
2024	0

1

Carbapenems against Mycobacterium tuberculosis: a review of the evidence.

Jaganath D, Lamichhane G, Shah M. Jaganath D, et al. Int J Tuberc Lung Dis. 2016 Nov;20(11):1436-1447. doi: 10.5588/ijtld.16.0498. Int J Tuberc Lung Dis. 2016. PMID: 27776583 Review.

2

Structural and functional features of enzymes of Mycobacterium tuberculosis peptidoglycan biosynthesis as targets for drug development.

Moraes GL, Gomes GC, Monteiro de Sousa PR, Alves CN, Govender T, Kruger HG, Maguire GE, Lamichhane G, Lameira J. Moraes GL, et al. Tuberculosis (Edinb). 2015 Mar;95(2):95-111. doi: 10.1016/j.tube.2015.01.006. Epub 2015 Jan 29. Tuberculosis (Edinb). 2015. PMID: 25701501 Free PMC article. Review.

3

Non-classical transpeptidases yield insight into new antibacterials.

Kumar P, Kaushik A, Lloyd EP, Li SG, Mattoo R, Ammerman NC, Bell DT, Perryman AL, Zandi TA, Ekins S, Ginell SL, Townsend CA, Freundlich JS, Lamichhane G. Kumar P, et al. Nat Chem Biol. 2017 Jan;13(1):54-61. doi: 10.1038/nchembio.2237. Epub 2016 Nov 7. Nat Chem Biol. 2017. PMID: 27820797 Free PMC article.

4

Ldt_Mav2, a nonclassical transpeptidase and susceptibility of Mycobacterium avium to carbapenems.

Mattoo R, Lloyd EP, Kaushik A, Kumar P, Brunelle JL, Townsend CA, Lamichhane G. Mattoo R, et al. Future Microbiol. 2017 Jun;12(7):595-607. doi: 10.2217/fmb-2016-0208. Epub 2017 May 30. Future Microbiol. 2017. PMID: 28555497 Free PMC article.

5

In vitro and in vivo activity of biapenem against drug-susceptible and rifampicin-resistant Mycobacterium tuberculosis.

Kaushik A, Ammerman NC, Tasneen R, Story-Roller E, Dooley KE, Dorman SE, Nuermberger EL, Lamichhane G. Kaushik A, et al. J Antimicrob Chemother. 2017 Aug 1;72(8):2320-2325. doi: 10.1093/jac/dkx152. J Antimicrob Chemother. 2017. PMID: 28575382 Free PMC article.

6

Intrabacterial Metabolism Obscures the Successful Prediction of an InhA Inhibitor of Mycobacterium tuberculosis.

Wang X, Perryman AL, Li SG, Paget SD, Stratton TP, Lemenze A, Olson AJ, Ekins S, Kumar P, Freundlich JS. Wang X, et al. ACS Infect Dis. 2019 Dec 13;5(12):2148-2163. doi: 10.1021/acsinfecdis.9b00295. Epub 2019 Nov 5. ACS Infect Dis. 2019. PMID: 31625383 Free PMC article.

7

Pyrazinoic Acid Inhibits a Bifunctional Enzyme in Mycobacterium tuberculosis.

Njire M, Wang N, Wang B, Tan Y, Cai X, Liu Y, Mugweru J, Guo J, Hameed HMA, Tan S, Liu J, Yew WW, Nuermberger E, Lamichhane G, Liu J, Zhang T. Njire M, et al. Antimicrob Agents Chemother. 2017 Jun 27;61(7):e00070-17. doi: 10.1128/AAC.00070-17. Print 2017 Jul. Antimicrob Agents Chemother. 2017. PMID: 28438933 Free PMC article.

8

REMap: Operon map of M. tuberculosis based on RNA sequence data.

Pelly S, Winglee K, Xia FF, Stevens RL, Bishai WR, Lamichhane G. Pelly S, et al. Tuberculosis (Edinb). 2016 Jul;99:70-80. doi: 10.1016/j.tube.2016.04.010. Epub 2016 Apr 29. Tuberculosis (Edinb). 2016. PMID: 27450008 Free PMC article.

9

Loss of a Functionally and Structurally Distinct ld-Transpeptidase, LdtMt5, Compromises Cell Wall Integrity in Mycobacterium tuberculosis.

Brammer Basta LA, Ghosh A, Pan Y, Jakoncic J, Lloyd EP, Townsend CA, Lamichhane G, Bianchet MA. Brammer Basta LA, et al. J Biol Chem. 2015 Oct 16;290(42):25670-85. doi: 10.1074/jbc.M115.660753. Epub 2015 Aug 24. J Biol Chem. 2015. PMID: 26304120 Free PMC article.

10

Structural insight into the inactivation of Mycobacterium tuberculosis non-classical transpeptidase Ldt_Mt2 by biapenem and tebipenem.

Bianchet MA, Pan YH, Basta LAB, Saavedra H, Lloyd EP, Kumar P, Mattoo R, Townsend CA, Lamichhane G. Bianchet MA, et al. BMC Biochem. 2017 May 25;18(1):8. doi: 10.1186/s12858-017-0082-4. BMC Biochem. 2017. PMID: 28545389 Free PMC article.

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