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Table representation of search results timeline featuring number of search results per year.
Year | Number of Results |
---|---|
2012 | 1 |
2013 | 1 |
2014 | 2 |
2015 | 1 |
2016 | 1 |
2024 | 0 |
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5 results
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Page 1
Drugging the undruggable RAS: Mission possible?
Nat Rev Drug Discov. 2014 Nov;13(11):828-51. doi: 10.1038/nrd4389. Epub 2014 Oct 17.
Nat Rev Drug Discov. 2014.
PMID: 25323927
Free PMC article.
Review.
Discovery of 2-Indole-acylsulfonamide Myeloid Cell Leukemia 1 (Mcl-1) Inhibitors Using Fragment-Based Methods.
Pelz NF, Bian Z, Zhao B, Shaw S, Tarr JC, Belmar J, Gregg C, Camper DV, Goodwin CM, Arnold AL, Sensintaffar JL, Friberg A, Rossanese OW, Lee T, Olejniczak ET, Fesik SW.
Pelz NF, et al.
J Med Chem. 2016 Mar 10;59(5):2054-66. doi: 10.1021/acs.jmedchem.5b01660. Epub 2016 Feb 24.
J Med Chem. 2016.
PMID: 26878343
Free PMC article.
Item in Clipboard
Discovery of tricyclic indoles that potently inhibit Mcl-1 using fragment-based methods and structure-based design.
Burke JP, Bian Z, Shaw S, Zhao B, Goodwin CM, Belmar J, Browning CF, Vigil D, Friberg A, Camper DV, Rossanese OW, Lee T, Olejniczak ET, Fesik SW.
Burke JP, et al.
J Med Chem. 2015 May 14;58(9):3794-805. doi: 10.1021/jm501984f. Epub 2015 Apr 17.
J Med Chem. 2015.
PMID: 25844895
Free PMC article.
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Discovery of potent myeloid cell leukemia 1 (Mcl-1) inhibitors using fragment-based methods and structure-based design.
Friberg A, Vigil D, Zhao B, Daniels RN, Burke JP, Garcia-Barrantes PM, Camper D, Chauder BA, Lee T, Olejniczak ET, Fesik SW.
Friberg A, et al.
J Med Chem. 2013 Jan 10;56(1):15-30. doi: 10.1021/jm301448p. Epub 2012 Dec 17.
J Med Chem. 2013.
PMID: 23244564
Free PMC article.
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A method for the second-site screening of K-Ras in the presence of a covalently attached first-site ligand.
Sun Q, Phan J, Friberg AR, Camper DV, Olejniczak ET, Fesik SW.
Sun Q, et al.
J Biomol NMR. 2014 Sep;60(1):11-4. doi: 10.1007/s10858-014-9849-8. Epub 2014 Aug 3.
J Biomol NMR. 2014.
PMID: 25087006
Free PMC article.
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