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A possible role for intracellular GSH in spontaneous reaction of a cysteine (T338C) engineered into the Cystic Fibrosis Transmembrane Conductance Regulator.
Biometals. 2008 Jun;21(3):277-87. doi: 10.1007/s10534-007-9117-4. Epub 2007 Sep 12.
Biometals. 2008.
PMID: 17849169
Cystic fibrosis transmembrane conductance regulator: using differential reactivity toward channel-permeant and channel-impermeant thiol-reactive probes to test a molecular model for the pore.
Alexander C, Ivetac A, Liu X, Norimatsu Y, Serrano JR, Landstrom A, Sansom M, Dawson DC.
Alexander C, et al.
Biochemistry. 2009 Oct 27;48(42):10078-88. doi: 10.1021/bi901314c.
Biochemistry. 2009.
PMID: 19754156
Free PMC article.
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Variable reactivity of an engineered cysteine at position 338 in cystic fibrosis transmembrane conductance regulator reflects different chemical states of the thiol.
Liu X, Alexander C, Serrano J, Borg E, Dawson DC.
Liu X, et al.
J Biol Chem. 2006 Mar 24;281(12):8275-85. doi: 10.1074/jbc.M512458200. Epub 2006 Jan 24.
J Biol Chem. 2006.
PMID: 16436375
Free article.
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