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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1877 1
1889 2
1890 1
1893 1
1894 1
1896 1
1899 1
1900 1
1902 1
1903 2
1906 1
1907 3
1909 1
1911 1
1915 3
1917 1
1918 1
1920 1
1922 5
1924 3
1925 5
1926 1
1927 7
1928 2
1929 4
1931 2
1932 2
1934 2
1935 1
1936 2
1938 1
1939 1
1942 3
1944 1
1945 3
1946 6
1947 6
1948 7
1949 9
1950 16
1951 18
1952 11
1953 10
1954 10
1955 9
1956 9
1957 9
1958 21
1959 8
1960 8
1961 15
1962 12
1963 14
1964 22
1965 35
1966 43
1967 61
1968 43
1969 44
1970 43
1971 53
1972 48
1973 51
1974 30
1975 117
1976 107
1977 121
1978 116
1979 128
1980 132
1981 133
1982 147
1983 201
1984 200
1985 219
1986 291
1987 357
1988 388
1989 444
1990 459
1991 432
1992 455
1993 445
1994 419
1995 413
1996 462
1997 417
1998 431
1999 439
2000 511
2001 553
2002 548
2003 653
2004 691
2005 844
2006 876
2007 1013
2008 1288
2009 1392
2010 1546
2011 1679
2012 1954
2013 2175
2014 2536
2015 2913
2016 3375
2017 3572
2018 3859
2019 3928
2020 4373
2021 4780
2022 4479
2023 4344
2024 1971

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57,711 results

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Page 1
Augmented Renal Clearance.
Cook AM, Hatton-Kolpek J. Cook AM, et al. Pharmacotherapy. 2019 Mar;39(3):346-354. doi: 10.1002/phar.2231. Epub 2019 Mar 11. Pharmacotherapy. 2019. PMID: 30723936 Review.
Augmented renal clearance (ARC) is a phenomenon in critically ill patients characterized by increased creatinine clearance and elimination of renally eliminated medications. ...Optimizing dosing strategies in critically ill patients with ARC remains a goal of contin …
Augmented renal clearance (ARC) is a phenomenon in critically ill patients characterized by increased creatinine clearance and elimin …
'Arc'-hitecture of normal cognitive aging.
Myrum C, Moreno-Castilla P, Rapp PR. Myrum C, et al. Ageing Res Rev. 2022 Sep;80:101678. doi: 10.1016/j.arr.2022.101678. Epub 2022 Jul 1. Ageing Res Rev. 2022. PMID: 35781092 Free PMC article. Review.
Arc is an effector immediate-early gene that is critical for forming long-term memories. ...In addition, we raise several outstanding questions, including whether Arc-containing EVs in peripheral blood might provide a noninvasive biomarker for memory-related synapti …
Arc is an effector immediate-early gene that is critical for forming long-term memories. ...In addition, we raise several outstanding …
Arc ubiquitination in synaptic plasticity.
Mabb AM, Ehlers MD. Mabb AM, et al. Semin Cell Dev Biol. 2018 May;77:10-16. doi: 10.1016/j.semcdb.2017.09.009. Epub 2017 Sep 7. Semin Cell Dev Biol. 2018. PMID: 28890418 Review.
Notably, Arc protein expression abruptly increases and then rapidly decreases following augmented network activity. A large body of work has focused on Arc transcription and translation. Far fewer studies have explored the relevance of Arc protein stability a …
Notably, Arc protein expression abruptly increases and then rapidly decreases following augmented network activity. A large body of w …
Effect of pharmacological manipulations on Arc function.
Yakout DW, Shree N, Mabb AM. Yakout DW, et al. Curr Res Pharmacol Drug Discov. 2020 Dec 24;2:100013. doi: 10.1016/j.crphar.2020.100013. eCollection 2021. Curr Res Pharmacol Drug Discov. 2020. PMID: 34909648 Free PMC article. Review.
Activity-regulated cytoskeleton-associated protein (Arc) is a brain-enriched immediate early gene that regulates important mechanisms implicated in learning and memory. ...Arc further undergoes multiple post-translational modifications that regulate its stabi …
Activity-regulated cytoskeleton-associated protein (Arc) is a brain-enriched immediate early gene that regulates important mec …
Arc - An endogenous neuronal retrovirus?
Shepherd JD. Shepherd JD. Semin Cell Dev Biol. 2018 May;77:73-78. doi: 10.1016/j.semcdb.2017.09.029. Epub 2017 Sep 24. Semin Cell Dev Biol. 2018. PMID: 28941877 Free PMC article. Review.
The neuronal gene Arc is essential for long-lasting information storage in the mammalian brain and has been implicated in various neurological disorders. However, little is known about Arc's evolutionary origins. Recent studies suggest that mammalian Arc …
The neuronal gene Arc is essential for long-lasting information storage in the mammalian brain and has been implicated in vari …
Membrane Remodeling by Arc/Arg3.1.
Hedde PN, Malacrida L, Barylko B, Binns DD, Albanesi JP, Jameson DM. Hedde PN, et al. Front Mol Biosci. 2021 Mar 8;8:630625. doi: 10.3389/fmolb.2021.630625. eCollection 2021. Front Mol Biosci. 2021. PMID: 33763452 Free PMC article.
The best-characterized cellular function of Arc is enhancement of the endocytic internalization of AMPA receptors (AMPARs) in dendritic spines. ...It was subsequently shown that Arc assembles into viral capsid-like structures that enclose Arc mRNA, are …
The best-characterized cellular function of Arc is enhancement of the endocytic internalization of AMPA receptors (AMPARs) in …
Arc Regulates Transcription of Genes for Plasticity, Excitability and Alzheimer's Disease.
Leung HW, Foo G, VanDongen A. Leung HW, et al. Biomedicines. 2022 Aug 11;10(8):1946. doi: 10.3390/biomedicines10081946. Biomedicines. 2022. PMID: 36009494 Free PMC article.
The immediate early gene Arc is a master regulator of synaptic function and a critical determinant of memory consolidation. ...When endogenous Arc expression was induced in HEK293T cells, the transcription of many neuronal genes was increased, suggesting that …
The immediate early gene Arc is a master regulator of synaptic function and a critical determinant of memory consolidation. .. …
Single-Arc IMRT?
Bortfeld T, Webb S. Bortfeld T, et al. Phys Med Biol. 2009 Jan 7;54(1):N9-20. doi: 10.1088/0031-9155/54/1/N02. Epub 2008 Dec 10. Phys Med Biol. 2009. PMID: 19075362
The idea of delivering intensity-modulated radiation therapy (IMRT) with a multileaf collimator in a continuous dynamic mode during a single rotation of the gantry has recently gained momentum both in research and industry. In this note we investigate the potential of this …
The idea of delivering intensity-modulated radiation therapy (IMRT) with a multileaf collimator in a continuous dynamic mode during a single …
Molecular physiology of Arc/Arg3.1: The oligomeric state hypothesis of synaptic plasticity.
Eriksen MS, Bramham CR. Eriksen MS, et al. Acta Physiol (Oxf). 2022 Nov;236(3):e13886. doi: 10.1111/apha.13886. Epub 2022 Sep 20. Acta Physiol (Oxf). 2022. PMID: 36073248 Free PMC article. Review.
Here, we discuss recent findings on Arc structure-function and regulation of oligomerization that are giving insight into the molecular physiology of Arc. ...As the functional states of Arc are revealed, it may be possible to selectively …
Here, we discuss recent findings on Arc structure-function and regulation of oligomerization that are giving insight into the …
Transcriptomic and Proteomic Analysis of CRISPR/Cas9-Mediated ARC-Knockout HEK293 Cells.
Wang YY, Hsu SH, Tsai HY, Cheng FY, Cheng MC. Wang YY, et al. Int J Mol Sci. 2022 Apr 19;23(9):4498. doi: 10.3390/ijms23094498. Int J Mol Sci. 2022. PMID: 35562887 Free PMC article.
The functions and mechanisms of human ARC action are poorly understood and worthy of further investigation. To investigate the function of the ARC gene in vitro, we generated an ARC-knockout (KO) HEK293 cell line via CRISPR/Cas9-mediated gene ed …
The functions and mechanisms of human ARC action are poorly understood and worthy of further investigation. To investigate the …
57,711 results
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