BB/T015853/1/BB_/Biotechnology and Biological Sciences Research Council/United Kingdom[Grants and Funding] - Search Results

Year	Number of Results
2020	1
2021	3
2022	6
2023	5
2024	1

1

NAADP-binding proteins find their identity.

Marchant JS, Gunaratne GS, Cai X, Slama JT, Patel S. Marchant JS, et al. Trends Biochem Sci. 2022 Mar;47(3):235-249. doi: 10.1016/j.tibs.2021.10.008. Epub 2021 Nov 20. Trends Biochem Sci. 2022. PMID: 34810081 Free PMC article. Review.

2

Discovery of lipophilic two-pore channel agonists.

Gerndt S, Krogsaeter E, Patel S, Bracher F, Grimm C. Gerndt S, et al. FEBS J. 2020 Dec;287(24):5284-5293. doi: 10.1111/febs.15432. Epub 2020 Jun 14. FEBS J. 2020. PMID: 32478984 Free article. Review.

3

Segregated cation flux by TPC2 biases Ca²⁺ signaling through lysosomes.

Yuan Y, Jaślan D, Rahman T, Bolsover SR, Arige V, Wagner LE 2nd, Abrahamian C, Tang R, Keller M, Hartmann J, Rosato AS, Weiden EM, Bracher F, Yule DI, Grimm C, Patel S. Yuan Y, et al. Nat Commun. 2022 Aug 2;13(1):4481. doi: 10.1038/s41467-022-31959-0. Nat Commun. 2022. PMID: 35918320 Free PMC article.

4

Electrophysiology of Endolysosomal Two-Pore Channels: A Current Account.

Patel S, Yuan Y, Chen CC, Jaślan D, Gunaratne G, Grimm C, Rahman T, Marchant JS. Patel S, et al. Cells. 2022 Aug 2;11(15):2368. doi: 10.3390/cells11152368. Cells. 2022. PMID: 35954212 Free PMC article. Review.

5

Convergent activation of Ca²⁺ permeability in two-pore channel 2 through distinct molecular routes.

Saito R, Mu Q, Yuan Y, Rubio-Alarcón M, Eznarriaga M, Zhao P, Gunaratne G, Kumar S, Keller M, Bracher F, Grimm C, Brailoiu E, Marchant JS, Rahman T, Patel S. Saito R, et al. Sci Signal. 2023 Aug 22;16(799):eadg0661. doi: 10.1126/scisignal.adg0661. Epub 2023 Aug 22. Sci Signal. 2023. PMID: 37607219 Free PMC article.

6

New insights into gating mechanisms in TPCs: Relevance for drug discovery.

Jaślan D, Patel S, Grimm C. Jaślan D, et al. Cell Calcium. 2023 Jun;112:102732. doi: 10.1016/j.ceca.2023.102732. Epub 2023 Apr 5. Cell Calcium. 2023. PMID: 37031661 Review. No abstract available.

7

Convergent activation of two-pore channels mediated by the NAADP-binding proteins JPT2 and LSM12.

Gunaratne GS, Brailoiu E, Kumar S, Yuan Y, Slama JT, Walseth TF, Patel S, Marchant JS. Gunaratne GS, et al. Sci Signal. 2023 Aug 22;16(799):eadg0485. doi: 10.1126/scisignal.adg0485. Epub 2023 Aug 22. Sci Signal. 2023. PMID: 37607218 Free PMC article.

8

Activation of endo-lysosomal two-pore channels by NAADP and PI(3,5)P₂. Five things to know.

Patel S, Yuan Y, Gunaratne GS, Rahman T, Marchant JS. Patel S, et al. Cell Calcium. 2022 May;103:102543. doi: 10.1016/j.ceca.2022.102543. Epub 2022 Jan 25. Cell Calcium. 2022. PMID: 35123238 Free PMC article. Review.

9

Use of aequorin-based indicators for monitoring Ca²⁺ in acidic organelles.

Alonso MT, Torres-Vidal P, Calvo B, Rodriguez C, Delrio-Lorenzo A, Rojo-Ruiz J, Garcia-Sancho J, Patel S. Alonso MT, et al. Biochim Biophys Acta Mol Cell Res. 2023 Aug;1870(6):119481. doi: 10.1016/j.bbamcr.2023.119481. Epub 2023 May 2. Biochim Biophys Acta Mol Cell Res. 2023. PMID: 37142127 Free article. Review.

10

Rendezvous with PI(3,5)P₂ - A rapalog gets caught opening TRPML1.

Rahman T, Patel S. Rahman T, et al. Cell Calcium. 2022 Jul;105:102597. doi: 10.1016/j.ceca.2022.102597. Epub 2022 May 14. Cell Calcium. 2022. PMID: 35596965

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