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Mitochondrial genetic variation is enriched in G-quadruplex regions that stall DNA synthesis in vitro.
Butler TJ, Estep KN, Sommers JA, Maul RW, Moore AZ, Bandinelli S, Cucca F, Tuke MA, Wood AR, Bharti SK, Bogenhagen DF, Yakubovskaya E, Garcia-Diaz M, Guilliam TA, Byrd AK, Raney KD, Doherty AJ, Ferrucci L, Schlessinger D, Ding J, Brosh RM. Butler TJ, et al. Hum Mol Genet. 2020 May 28;29(8):1292-1309. doi: 10.1093/hmg/ddaa043. Hum Mol Genet. 2020. PMID: 32191790 Free PMC article.
PDIP38/PolDIP2 controls the DNA damage tolerance pathways by increasing the relative usage of translesion DNA synthesis over template switching.
Tsuda M, Ogawa S, Ooka M, Kobayashi K, Hirota K, Wakasugi M, Matsunaga T, Sakuma T, Yamamoto T, Chikuma S, Sasanuma H, Debatisse M, Doherty AJ, Fuchs RP, Takeda S. Tsuda M, et al. PLoS One. 2019 Mar 6;14(3):e0213383. doi: 10.1371/journal.pone.0213383. eCollection 2019. PLoS One. 2019. PMID: 30840704 Free PMC article.