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Constitutively active Rheb mutants [T23M] and [E40K] drive increased production and secretion of recombinant protein in Chinese hamster ovary cells.
Biotechnol Bioeng. 2021 Jul;118(7):2422-2434. doi: 10.1002/bit.27748. Epub 2021 Apr 14.
Biotechnol Bioeng. 2021.
PMID: 33694218
The MAP kinase-interacting kinases regulate cell migration, vimentin expression and eIF4E/CYFIP1 binding.
Beggs JE, Tian S, Jones GG, Xie J, Iadevaia V, Jenei V, Thomas G, Proud CG.
Beggs JE, et al.
Biochem J. 2015 Apr 1;467(1):63-76. doi: 10.1042/BJ20141066.
Biochem J. 2015.
PMID: 25588502
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Eukaryotic elongation factor 2 kinase activity is controlled by multiple inputs from oncogenic signaling.
Wang X, Regufe da Mota S, Liu R, Moore CE, Xie J, Lanucara F, Agarwala U, Pyr Dit Ruys S, Vertommen D, Rider MH, Eyers CE, Proud CG.
Wang X, et al.
Mol Cell Biol. 2014 Nov 15;34(22):4088-103. doi: 10.1128/MCB.01035-14. Epub 2014 Sep 2.
Mol Cell Biol. 2014.
PMID: 25182533
Free PMC article.
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Elongation factor 2 kinase promotes cell survival by inhibiting protein synthesis without inducing autophagy.
Moore CE, Wang X, Xie J, Pickford J, Barron J, Regufe da Mota S, Versele M, Proud CG.
Moore CE, et al.
Cell Signal. 2016 Apr;28(4):284-93. doi: 10.1016/j.cellsig.2016.01.005. Epub 2016 Jan 18.
Cell Signal. 2016.
PMID: 26795954
Free PMC article.
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