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Prevalence and speciation of brucellosis in febrile patients from a pastoralist community of Tanzania.
Bodenham RF, Lukambagire AS, Ashford RT, Buza JJ, Cash-Goldwasser S, Crump JA, Kazwala RR, Maro VP, McGiven J, Mkenda N, Mmbaga BT, Rubach MP, Sakasaka P, Shirima GM, Swai ES, Thomas KM, Whatmore AM, Haydon DT, Halliday JEB. Bodenham RF, et al. Sci Rep. 2020 Apr 27;10(1):7081. doi: 10.1038/s41598-020-62849-4. Sci Rep. 2020. PMID: 32341414 Free PMC article. Clinical Trial.
Brucella spp. was the most common bloodstream infection, with B. melitensis isolated from seven participants and B. abortus from one. ...Livestock vaccination strategies for the region should include both B. melitensis and B. abortus....
Brucella spp. was the most common bloodstream infection, with B. melitensis isolated from seven participants and B. abortus fr …
Population genomics of Bacillus anthracis from an anthrax hyperendemic area reveals transmission processes across spatial scales and unexpected within-host diversity.
Forde TL, Dennis TPW, Aminu OR, Harvey WT, Hassim A, Kiwelu I, Medvecky M, Mshanga D, Van Heerden H, Vogel A, Zadoks RN, Mmbaga BT, Lembo T, Biek R. Forde TL, et al. Microb Genom. 2022 Feb;8(2):000759. doi: 10.1099/mgen.0.000759. Microb Genom. 2022. PMID: 35188453 Free PMC article.
Genome-wide SNPs distinguished 22 unique B. anthracis genotypes (i.e. SNP profiles) within the study area. ...This points to an unexpectedly wide transmission bottleneck for B. anthracis, with an inoculum comprising multiple variants being the norm. ...
Genome-wide SNPs distinguished 22 unique B. anthracis genotypes (i.e. SNP profiles) within the study area. ...This points to an unexp …
Investigation of Melioidosis Using Blood Culture and Indirect Hemagglutination Assay Serology among Patients with Fever, Northern Tanzania.
Maze MJ, Elrod MG, Biggs HM, Bonnewell J, Carugati M, Hoffmaster AR, Lwezaula BF, Madut DB, Maro VP, Mmbaga BT, Morrissey AB, Saganda W, Sakasaka P, Rubach MP, Crump JA. Maze MJ, et al. Am J Trop Med Hyg. 2020 Dec;103(6):2510-2514. doi: 10.4269/ajtmh.20-0160. Epub 2020 Sep 24. Am J Trop Med Hyg. 2020. PMID: 32996455 Free PMC article.
We defined confirmed melioidosis as isolation of B. pseudomallei from blood culture, probable melioidosis as a 4-fold rise in antibody titers between acute and convalescent sera, and seropositivity as a single antibody titer 40. We enrolled 3,716 participants and isolated …
We defined confirmed melioidosis as isolation of B. pseudomallei from blood culture, probable melioidosis as a 4-fold rise in antibod …