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Page 1
Design, Synthesis, and Pharmacological Characterization of 2-(2-Furanyl)thiazolo[5,4-d]pyrimidine-5,7-diamine Derivatives: New Highly Potent A2A Adenosine Receptor Inverse Agonists with Antinociceptive Activity.
Varano F, Catarzi D, Vincenzi F, Betti M, Falsini M, Ravani A, Borea PA, Colotta V, Varani K. Varano F, et al. Among authors: ravani a. J Med Chem. 2016 Dec 8;59(23):10564-10576. doi: 10.1021/acs.jmedchem.6b01068. Epub 2016 Nov 29. J Med Chem. 2016. PMID: 27933962
Dopamine D2 receptor signaling dynamics of dopamine D2-neurotensin 1 receptor heteromers.
Borroto-Escuela DO, Ravani A, Tarakanov AO, Brito I, Narvaez M, Romero-Fernandez W, Corrales F, Agnati LF, Tanganelli S, Ferraro L, Fuxe K. Borroto-Escuela DO, et al. Among authors: ravani a. Biochem Biophys Res Commun. 2013 May 24;435(1):140-6. doi: 10.1016/j.bbrc.2013.04.058. Epub 2013 Apr 25. Biochem Biophys Res Commun. 2013. PMID: 23624386
Exploring the 7-oxo-thiazolo[5,4-d]pyrimidine core for the design of new human adenosine A3 receptor antagonists. Synthesis, molecular modeling studies and pharmacological evaluation.
Varano F, Catarzi D, Squarcialupi L, Betti M, Vincenzi F, Ravani A, Varani K, Dal Ben D, Thomas A, Volpini R, Colotta V. Varano F, et al. Among authors: ravani a. Eur J Med Chem. 2015;96:105-21. doi: 10.1016/j.ejmech.2015.04.010. Epub 2015 Apr 4. Eur J Med Chem. 2015. PMID: 25874336
Repeated Dosing with NCX1404, a Nitric Oxide-Donating Pregabalin, Re-establishes Normal Nociceptive Responses in Mice with Streptozotocin-Induced Painful Diabetic Neuropathy.
Varani K, Vincenzi F, Targa M, Ravani A, Bastia E, Storoni L, Brambilla S, Almirante N, Impagnatiello F. Varani K, et al. Among authors: ravani a. J Pharmacol Exp Ther. 2016 May;357(2):240-7. doi: 10.1124/jpet.115.230193. Epub 2016 Feb 23. J Pharmacol Exp Ther. 2016. PMID: 26907623
The role of 5-arylalkylamino- and 5-piperazino- moieties on the 7-aminopyrazolo[4,3-d]pyrimidine core in affecting adenosine A1 and A2A receptor affinity and selectivity profiles.
Squarcialupi L, Betti M, Catarzi D, Varano F, Falsini M, Ravani A, Pasquini S, Vincenzi F, Salmaso V, Sturlese M, Varani K, Moro S, Colotta V. Squarcialupi L, et al. Among authors: ravani a. J Enzyme Inhib Med Chem. 2017 Dec;32(1):248-263. doi: 10.1080/14756366.2016.1247060. J Enzyme Inhib Med Chem. 2017. PMID: 28114825 Free PMC article.
14 results