AI53825/AI/NIAID NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2003	1
2004	4
2005	2
2006	1
2007	2
2008	2
2009	3
2010	1
2012	2
2014	1
2015	1
2016	1
2024	0

1

TLR-driven early glycolytic reprogramming via the kinases TBK1-IKKɛ supports the anabolic demands of dendritic cell activation.

Everts B, Amiel E, Huang SC, Smith AM, Chang CH, Lam WY, Redmann V, Freitas TC, Blagih J, van der Windt GJ, Artyomov MN, Jones RG, Pearce EL, Pearce EJ. Everts B, et al. Nat Immunol. 2014 Apr;15(4):323-32. doi: 10.1038/ni.2833. Epub 2014 Feb 23. Nat Immunol. 2014. PMID: 24562310 Free PMC article.

2

Review series on helminths, immune modulation and the hygiene hypothesis: mechanisms underlying helminth modulation of dendritic cell function.

Carvalho L, Sun J, Kane C, Marshall F, Krawczyk C, Pearce EJ. Carvalho L, et al. Immunology. 2009 Jan;126(1):28-34. doi: 10.1111/j.1365-2567.2008.03008.x. Immunology. 2009. PMID: 19120496 Free PMC article. Review.

3

Regulation of dendritic cell function by pathogen-derived molecules plays a key role in dictating the outcome of the adaptive immune response.

Pearce EJ, Kane CM, Sun J. Pearce EJ, et al. Chem Immunol Allergy. 2006;90:82-90. doi: 10.1159/000088882. Chem Immunol Allergy. 2006. PMID: 16210904 Review.

4

Cutting edge: dendritic cells copulsed with microbial and helminth antigens undergo modified maturation, segregate the antigens to distinct intracellular compartments, and concurrently induce microbe-specific Th1 and helminth-specific Th2 responses.

Cervi L, MacDonald AS, Kane C, Dzierszinski F, Pearce EJ. Cervi L, et al. J Immunol. 2004 Feb 15;172(4):2016-20. doi: 10.4049/jimmunol.172.4.2016. J Immunol. 2004. PMID: 14764665

5

Schistosome-derived omega-1 drives Th2 polarization by suppressing protein synthesis following internalization by the mannose receptor.

Everts B, Hussaarts L, Driessen NN, Meevissen MH, Schramm G, van der Ham AJ, van der Hoeven B, Scholzen T, Burgdorf S, Mohrs M, Pearce EJ, Hokke CH, Haas H, Smits HH, Yazdanbakhsh M. Everts B, et al. J Exp Med. 2012 Sep 24;209(10):1753-67, S1. doi: 10.1084/jem.20111381. Epub 2012 Sep 10. J Exp Med. 2012. PMID: 22966004 Free PMC article.

6

Migratory CD103+ dendritic cells suppress helminth-driven type 2 immunity through constitutive expression of IL-12.

Everts B, Tussiwand R, Dreesen L, Fairfax KC, Huang SC, Smith AM, O'Neill CM, Lam WY, Edelson BT, Urban JF Jr, Murphy KM, Pearce EJ. Everts B, et al. J Exp Med. 2016 Jan 11;213(1):35-51. doi: 10.1084/jem.20150235. Epub 2015 Dec 28. J Exp Med. 2016. PMID: 26712805 Free PMC article.

7

Helminth antigens modulate TLR-initiated dendritic cell activation.

Kane CM, Cervi L, Sun J, McKee AS, Masek KS, Shapira S, Hunter CA, Pearce EJ. Kane CM, et al. J Immunol. 2004 Dec 15;173(12):7454-61. doi: 10.4049/jimmunol.173.12.7454. J Immunol. 2004. PMID: 15585871

8

Th1 and Th2 cells help CD8 T-cell responses.

Ekkens MJ, Shedlock DJ, Jung E, Troy A, Pearce EL, Shen H, Pearce EJ. Ekkens MJ, et al. Infect Immun. 2007 May;75(5):2291-6. doi: 10.1128/IAI.01328-06. Epub 2007 Feb 26. Infect Immun. 2007. PMID: 17325050 Free PMC article.

9

TLR ligands can activate dendritic cells to provide a MyD88-dependent negative signal for Th2 cell development.

Sun J, Walsh M, Villarino AV, Cervi L, Hunter CA, Choi Y, Pearce EJ. Sun J, et al. J Immunol. 2005 Jan 15;174(2):742-51. doi: 10.4049/jimmunol.174.2.742. J Immunol. 2005. PMID: 15634894

10

Toll-like receptor-induced changes in glycolytic metabolism regulate dendritic cell activation.

Krawczyk CM, Holowka T, Sun J, Blagih J, Amiel E, DeBerardinis RJ, Cross JR, Jung E, Thompson CB, Jones RG, Pearce EJ. Krawczyk CM, et al. Blood. 2010 Jun 10;115(23):4742-9. doi: 10.1182/blood-2009-10-249540. Epub 2010 Mar 29. Blood. 2010. PMID: 20351312 Free PMC article.

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