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Clinical response to nivolumab in an INI1-deficient pediatric chordoma correlates with immunogenic recognition of brachyury.
Williamson LM, Rive CM, Di Francesco D, Titmuss E, Chun HE, Brown SD, Milne K, Pleasance E, Lee AF, Yip S, Rosenbaum DG, Hasselblatt M, Johann PD, Kool M, Harvey M, Dix D, Renouf DJ, Holt RA, Nelson BH, Hirst M, Jones SJM, Laskin J, Rassekh SR, Deyell RJ, Marra MA. Williamson LM, et al. NPJ Precis Oncol. 2021 Dec 20;5(1):103. doi: 10.1038/s41698-021-00238-4. NPJ Precis Oncol. 2021. PMID: 34931022 Free PMC article.
MAIT cells accumulate in ovarian cancer-elicited ascites where they retain their capacity to respond to MR1 ligands and cytokine cues.
Yao T, Rudak PT, Laumont CM, Michaud AR, Rashu R, Knier NN, Foster PJ, McWilliam HEG, Villadangos JA, Nelson BH, DiMattia GE, Shepherd TG, Haeryfar SMM. Yao T, et al. Cancer Immunol Immunother. 2022 May;71(5):1259-1273. doi: 10.1007/s00262-021-03118-9. Epub 2021 Dec 2. Cancer Immunol Immunother. 2022. PMID: 34854949 Free PMC article.