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2019 8
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2023 12
2024 3

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Page 1
Polθ inhibitors elicit BRCA-gene synthetic lethality and target PARP inhibitor resistance.
Zatreanu D, Robinson HMR, Alkhatib O, Boursier M, Finch H, Geo L, Grande D, Grinkevich V, Heald RA, Langdon S, Majithiya J, McWhirter C, Martin NMB, Moore S, Neves J, Rajendra E, Ranzani M, Schaedler T, Stockley M, Wiggins K, Brough R, Sridhar S, Gulati A, Shao N, Badder LM, Novo D, Knight EG, Marlow R, Haider S, Callen E, Hewitt G, Schimmel J, Prevo R, Alli C, Ferdinand A, Bell C, Blencowe P, Bot C, Calder M, Charles M, Curry J, Ekwuru T, Ewings K, Krajewski W, MacDonald E, McCarron H, Pang L, Pedder C, Rigoreau L, Swarbrick M, Wheatley E, Willis S, Wong AC, Nussenzweig A, Tijsterman M, Tutt A, Boulton SJ, Higgins GS, Pettitt SJ, Smith GCM, Lord CJ. Zatreanu D, et al. Nat Commun. 2021 Jun 17;12(1):3636. doi: 10.1038/s41467-021-23463-8. Nat Commun. 2021. PMID: 34140467 Free PMC article.
Small-Molecule Polθ Inhibitors Provide Safe and Effective Tumor Radiosensitization in Preclinical Models.
Rodriguez-Berriguete G, Ranzani M, Prevo R, Puliyadi R, Machado N, Bolland HR, Millar V, Ebner D, Boursier M, Cerutti A, Cicconi A, Galbiati A, Grande D, Grinkevich V, Majithiya JB, Piscitello D, Rajendra E, Stockley ML, Boulton SJ, Hammond EM, Heald RA, Smith GCM, Robinson HMR, Higgins GS. Rodriguez-Berriguete G, et al. Clin Cancer Res. 2023 Apr 14;29(8):1631-1642. doi: 10.1158/1078-0432.CCR-22-2977. Clin Cancer Res. 2023. PMID: 36689546 Free PMC article.
The National Cancer Research Institute Clinical and Translational Radiotherapy Research Working Group Workshop: Translating Novel Discoveries to and from the Clinic.
Chan Wah Hak C, Dean JA, Hill MA, Somaiah N; National Cancer Research Institute Clinical and Translational Radiotherapy Research Working Group 1(☆). Chan Wah Hak C, et al. Clin Oncol (R Coll Radiol). 2023 Dec;35(12):769-772. doi: 10.1016/j.clon.2023.08.011. Epub 2023 Sep 6. Clin Oncol (R Coll Radiol). 2023. PMID: 37741714 No abstract available.
Roadmap for precision preclinical x-ray radiation studies.
Verhaegen F, Butterworth KT, Chalmers AJ, Coppes RP, de Ruysscher D, Dobiasch S, Fenwick JD, Granton PV, Heijmans SHJ, Hill MA, Koumenis C, Lauber K, Marples B, Parodi K, Persoon LCGG, Staut N, Subiel A, Vaes RDW, van Hoof S, Verginadis IL, Wilkens JJ, Williams KJ, Wilson GD, Dubois LJ. Verhaegen F, et al. Phys Med Biol. 2023 Mar 31;68(6). doi: 10.1088/1361-6560/acaf45. Phys Med Biol. 2023. PMID: 36584393 Free article. Review.
Flow radiocytometry using droplet optofluidics.
Ha B, Kim TJ, Moon E, Giaccia AJ, Pratx G. Ha B, et al. Biosens Bioelectron. 2021 Dec 15;194:113565. doi: 10.1016/j.bios.2021.113565. Epub 2021 Aug 13. Biosens Bioelectron. 2021. PMID: 34492500 Free PMC article.
74 results