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Synthesis and Structural Optimization of 2,7,9-Trisubstituted purin-8-ones as FLT3-ITD Inhibitors.
Int J Mol Sci. 2022 Dec 18;23(24):16169. doi: 10.3390/ijms232416169.
Int J Mol Sci. 2022.
PMID: 36555810
Free PMC article.
Synthesis of 4-styrylpyrazoles and Evaluation of their Inhibitory Effects on Cyclin-dependent Kinases.
Toman D, Jorda R, Ajani H, Kryštof V, Cankař P.
Toman D, et al.
Med Chem. 2022;18(4):484-496. doi: 10.2174/1573406417666210806095710.
Med Chem. 2022.
PMID: 34365958
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Design, Synthesis, In Silico Studies and Inhibitory Activity towards Bcr-Abl, BTK and FLT3-ITD of New 2,6,9-Trisubstituted Purine Derivatives as Potential Agents for the Treatment of Leukaemia.
Bertrand J, Dostálová H, Kryštof V, Jorda R, Delgado T, Castro-Alvarez A, Mella J, Cabezas D, Faúndez M, Espinosa-Bustos C, Salas CO.
Bertrand J, et al.
Pharmaceutics. 2022 Jun 17;14(6):1294. doi: 10.3390/pharmaceutics14061294.
Pharmaceutics. 2022.
PMID: 35745866
Free PMC article.
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Adamantane-Substituted Purine Nucleosides: Synthesis, Host-Guest Complexes with β-Cyclodextrin and Biological Activity.
Rudolfová J, Kryštof V, Nečas M, Vícha R, Rouchal M.
Rudolfová J, et al.
Int J Mol Sci. 2022 Dec 1;23(23):15143. doi: 10.3390/ijms232315143.
Int J Mol Sci. 2022.
PMID: 36499470
Free PMC article.
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