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APOE ε4 is associated with decreased synaptic density in cognitively impaired participants.
Alzheimers Dement. 2024 May;20(5):3157-3166. doi: 10.1002/alz.13775. Epub 2024 Mar 13.
Alzheimers Dement. 2024.
PMID: 38477490
Free PMC article.
Presynaptic density determined by SV2A PET is closely associated with postsynaptic metabotropic glutamate receptor 5 availability and independent of amyloid pathology in early cognitive impairment.
Wang J, Huang Q, He K, Li J, Guo T, Yang Y, Lin Z, Li S, Vanderlinden G, Huang Y, Van Laere K, Guan Y, Guo Q, Ni R, Li B, Xie F.
Wang J, et al.
Alzheimers Dement. 2024 Apr 18. doi: 10.1002/alz.13817. Online ahead of print.
Alzheimers Dement. 2024.
PMID: 38634334
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