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Hydrophilic nanofibers with aligned topography modulate macrophage-mediated host responses via the NLRP3 inflammasome.
Ren Y, Chen Y, Chen W, Deng H, Li P, Liu Y, Gao C, Tian G, Ning C, Yuan Z, Sui X, Liu S, Guo Q. Ren Y, et al. J Nanobiotechnology. 2023 Aug 14;21(1):269. doi: 10.1186/s12951-023-02024-9. J Nanobiotechnology. 2023. PMID: 37574546 Free PMC article.
Successful biomaterial implantation requires appropriate immune responses. Macrophages are key mediators involved in this process. Currently, exploitation of the intrinsic properties of biomaterials to modulate macrophages and immune responses is appealing. ...
Successful biomaterial implantation requires appropriate immune responses. Macrophages are key mediators involved in this process. Cu …
Core Decompression with Local Administration of Zoledronate and Enriched Bone Marrow Mononuclear Cells for Treatment of Non-Traumatic Osteonecrosis of Femoral Head.
Ma HY, Ma N, Liu YF, Wan YQ, Liu GQ, Liu GB, Meng HY, Li H, Wang X, Li CB, Peng J. Ma HY, et al. Orthop Surg. 2021 Aug;13(6):1843-1852. doi: 10.1111/os.13100. Orthop Surg. 2021. PMID: 34664417 Free PMC article.
METHODS: A total of 17 patients (30 hips) diagnosed with stage II and III ONFH according to the 2019 revised Association for Research on Osseous Circulation (ARCO) staging criteria from 2012 to 2014 were retrospectively reviewed. ...
METHODS: A total of 17 patients (30 hips) diagnosed with stage II and III ONFH according to the 2019 revised Association for Research …
ZnO/Nanocarbons-Modified Fibrous Scaffolds for Stem Cell-Based Osteogenic Differentiation.
Xia Y, Fan X, Yang H, Li L, He C, Cheng C, Haag R. Xia Y, et al. Small. 2020 Sep;16(38):e2003010. doi: 10.1002/smll.202003010. Epub 2020 Aug 19. Small. 2020. PMID: 32815251
Currently, mesenchymal stem cells (MSCs)-based therapies for bone regeneration and treatments have gained significant attention in clinical research. Though many chemical and physical cues which influence the osteogenic differentiation of MSCs have been explored, scaffolds …
Currently, mesenchymal stem cells (MSCs)-based therapies for bone regeneration and treatments have gained significant attention in clinical …
Apoptotic extracellular vesicles derived from hypoxia-preconditioned mesenchymal stem cells within a modified gelatine hydrogel promote osteochondral regeneration by enhancing stem cell activity and regulating immunity.
Ding Z, Yan Z, Yuan X, Tian G, Wu J, Fu L, Yin H, He S, Ning C, Zheng Y, Zhang Z, Sui X, Hao L, Niu Y, Liu S, Guo W, Guo Q. Ding Z, et al. J Nanobiotechnology. 2024 Feb 23;22(1):74. doi: 10.1186/s12951-024-02333-7. J Nanobiotechnology. 2024. PMID: 38395929 Free PMC article.
MicroRNA-29c-tetrahedral framework nucleic acids: Towards osteogenic differentiation of mesenchymal stem cells and bone regeneration in critical-sized calvarial defects.
Sun J, Chen X, Lin Y, Cai X. Sun J, et al. Cell Prolif. 2024 Feb 27:e13624. doi: 10.1111/cpr.13624. Online ahead of print. Cell Prolif. 2024. PMID: 38414296
The development of this novel nucleic acid nano-carrier, stFNAs-miR29c, presents a potential new avenue for guided bone regeneration and bone tissue engineering research....
The development of this novel nucleic acid nano-carrier, stFNAs-miR29c, presents a potential new avenue for guided bone regeneration and bon …