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CD81 Enhances Radioresistance of Glioblastoma by Promoting Nuclear Translocation of Rad51.
Zheng W, Chen Q, Liu H, Hu S, Zhou Y, Bai Y, Zhang J, Pan Y, Shao C. Zheng W, et al. Cancers (Basel). 2021 Apr 21;13(9):1998. doi: 10.3390/cancers13091998. Cancers (Basel). 2021. PMID: 33919192 Free PMC article.
Mechanistically, we found that knockdown of CD81 significantly decreased radiation-induced expression of nuclear Rad51, a key protein involved in homologous recombination repair (HRR) of DNA, suggesting that CD81 is essential for DNA damage response. ...
Mechanistically, we found that knockdown of CD81 significantly decreased radiation-induced expression of nuclear Rad51, a key protein …
MMP14 Contributes to HDAC Inhibition-Induced Radiosensitization of Glioblastoma.
Zhou Y, Liu H, Zheng W, Chen Q, Hu S, Pan Y, Bai Y, Zhang J, Shao C. Zhou Y, et al. Int J Mol Sci. 2021 Sep 27;22(19):10403. doi: 10.3390/ijms221910403. Int J Mol Sci. 2021. PMID: 34638754 Free PMC article.
Radiotherapy has long been an important treatment method of GBM. However, the intrinsic radioresistance of GBM cells is a key reason of poor therapeutic efficiency. Recently, many studies have shown that using the histone deacetylase (HDAC) inhibitor suberoylanilide hydrox …
Radiotherapy has long been an important treatment method of GBM. However, the intrinsic radioresistance of GBM cells is a key reason …