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Differential mode of cholesterol inclusion with 2-hydroxypropyl-cyclodextrins increases safety margin in treatment of Niemann-Pick disease type C.
Br J Pharmacol. 2021 Jul;178(13):2727-2746. doi: 10.1111/bph.15464. Epub 2021 May 12.
Br J Pharmacol. 2021.
PMID: 33782944
Free article.
Intracerebroventricular Treatment with 2-Hydroxypropyl-β-Cyclodextrin Decreased Cerebellar and Hepatic Glycoprotein Nonmetastatic Melanoma Protein B (GPNMB) Expression in Niemann-Pick Disease Type C Model Mice.
Fukaura M, Ishitsuka Y, Shirakawa S, Ushihama N, Yamada Y, Kondo Y, Takeo T, Nakagata N, Motoyama K, Higashi T, Arima H, Kurauchi Y, Seki T, Katsuki H, Higaki K, Matsuo M, Irie T.
Fukaura M, et al.
Int J Mol Sci. 2021 Jan 5;22(1):452. doi: 10.3390/ijms22010452.
Int J Mol Sci. 2021.
PMID: 33466390
Free PMC article.
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